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  • SMX: A New Supply Chain Reality in the World’s Four Largest Markets

    SMX: A New Supply Chain Reality in the World’s Four Largest Markets

    NEW YORK, NY / ACCESS Newswire / December 16, 2025 / Most companies grow by drifting into adjacent markets. SMX (NASDAQ:SMX) never needed that playbook. The company built a molecular identity platform that operates above traditional industry lines, becoming the engine behind a new era of verifiable supply chain integrity.

    Gold provenance, rare earth mineral traceability, ESG credibility, and digital-asset creation are not separate strategies. They are all outputs of the same technological core, a system that allows materials to retain identity through every transformation. When that capability exists, markets that once lived in isolation begin moving around the same center of gravity.

    Four Markets, Four Supply Chain Target Opportunities

    Gold is the clearest example of what changes when identity becomes permanent. The bullion trade has relied on paperwork for centuries, even though paperwork evaporates the moment metal is heated or reshaped. Bars cross borders, enter vaults, pass through refiners, and lose their history along the way. SMX closed that gap by giving gold a molecular passport that survives smelting, recasting, storage, and transport. Authenticity no longer comes from documents. It comes from the metal itself.

    Rare earth minerals reveal a different side of the same transformation. These materials power clean energy, aerospace systems, robotics, and national defense, yet their supply chains remain some of the most opaque on Earth. Ores blend. Concentrates mix. Processing removes any visible signature of origin. SMX changes that. Rare earths can now carry identity from extraction to separation to alloy formation, giving governments, manufacturers, and critical-infrastructure providers verifiable lineage that survives every industrial stage.

    Sustainability markets face their own version of the challenge. ESG frameworks require recovery data, lifecycle clarity, and proof of recycled content, which have historically depended on inference. SMX replaces that guesswork. Plastics, textiles, chemicals, and industrial materials can retain identity from origin through end-of-life, converting ESG from a documentation ritual into measurable truth, all powered by the same platform already reshaping gold and rare earths.

    Identity Has No Boundaries

    That shared foundation becomes even more visible when digital markets enter the picture. Digital-asset systems have spent years searching for reliable links to real-world performance. SMX built that bridge. The Plastic Cycle Token (PCT) converts authenticated material activity into digital signals that carry scientific integrity. Verification becomes digital value.

    Across gold, rare earths, ESG, and digital assets, the bottleneck has always been the same: verification that survives transformation. SMX built the platform designed for that requirement.

    The PCT makes the convergence unmistakable. Verified recovery becomes data. Data becomes a signal. That signal becomes a digital asset with a verifiable value-based anchor. And the same backbone that powers the PCT is the one authenticating metals, minerals, and materials. Gold reframes authenticity. Rare earths reframe provenance. ESG reframes circularity. Digital assets reframe value. SMX becomes the architecture that binds them into a single continuum.

    These markets may appear unrelated, but their structural weaknesses overlap perfectly. Gold struggles with integrity after transformation. Rare earths struggle with origin clarity. ESG struggles with proving what happened between factory and recycler. Digital assets struggle with verification without distortion. SMX removes all four barriers with one cross-market identity system.

    Where the Market Takes It From Here

    This is why interest continues to expand. SMX is not telling separate stories. It is revealing one system that multiple industries now recognize as foundational. When materials hold their identity, assumptions fall away, and verification becomes routine instead of exceptional.

    What that means in terms of value will not be defined by SMX. Markets determine fair value, and that process is now unfolding across the sectors converging around this technology. As each adopts the platform, the market recalibrates what this system represents.

    SMX built the engine. The market is beginning to understand its reach…and will ultimately decide what that reach is worth.

    About SMX

    As global businesses face new and complex challenges relating to carbon neutrality and meeting new governmental and regional regulations and standards, SMX is able to offer players along the value chain access to its marking, tracking, measuring and digital platform technology to transition more successfully to a low-carbon economy.

    Forward-Looking Statements

    The information in this press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, statements regarding expectations, hopes, beliefs, intentions or strategies regarding the future. In addition, any statements that refer to projections, forecasts or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. The words “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “forecast,” “intends,” “may,” “will,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. Forward-looking statements in this press release may include, for example: successful launch and implementation of SMX’s joint projects with manufacturers and other supply chain participants of steel, rubber, plastic and other materials; changes in SMX’s strategy, future operations, financial position, estimated revenues and losses, projected costs, prospects and plans; SMX’s ability to develop and launch new products and services, including its planned Plastic Cycle Token; SMX’s ability to successfully and efficiently integrate future expansion plans and opportunities; SMX’s ability to grow its business in a cost-effective manner; SMX’s product development timeline and estimated research and development costs; the implementation, market acceptance and success of SMX’s business model; developments and projections relating to SMX’s competitors and industry; and SMX’s approach and goals with respect to technology. These forward-looking statements are based on information available as of the date of this press release, and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties. Accordingly, forward-looking statements should not be relied upon as representing views as of any subsequent date, and no obligation is undertaken to update forward-looking statements to reflect events or circumstances after the date they were made, whether as a result of new information, future events or otherwise, except as may be required under applicable securities laws. As a result of a number of known and unknown risks and uncertainties, actual results or performance may be materially different from those expressed or implied by these forward-looking statements. Some factors that could cause actual results to differ include: the ability to maintain the listing of the Company’s shares on Nasdaq; changes in applicable laws or regulations; the ability to implement business plans, forecasts, and other expectations, and identify and realize additional opportunities; the risk of downturns and the possibility of rapid change in the highly competitive industry in which SMX operates; the risk that SMX and its current and future collaborators are unable to successfully develop and commercialize SMX’s products or services, or experience significant delays in doing so; the risk that the Company may never achieve or sustain profitability; the risk that the Company will need to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; the risk that the Company experiences difficulties in managing its growth and expanding operations; the risk that third-party suppliers and manufacturers are not able to fully and timely meet their obligations; the risk that SMX is unable to secure or protect its intellectual property; the possibility that SMX may be adversely affected by other economic, business, and/or competitive factors; and other risks and uncertainties described in SMX’s filings from time to time with the Securities and Exchange Commission.

    EMAIL: info@securitymattersltd.com

    SOURCE: SMX (Security Matters) Public Limited

    View the original press release on ACCESS Newswire

  • Ara Karkazian Watch & Jewelry Company Highlights Expert Guidance on Selecting Meaningful Jewelry Gifts for Anniversaries

    Ara Karkazian Watch & Jewelry Company Highlights Expert Guidance on Selecting Meaningful Jewelry Gifts for Anniversaries

    FRESNO, CA – December 05, 2025 – PRESSADVANTAGE –

    Ara Karkazian Watch & Jewelry Company has shared comprehensive insights into choosing jewelry as gifts to mark significant relationship milestones, drawing from decades of experience in the industry. This guidance emphasizes the role of precious items in symbolizing enduring commitments, with recommendations tailored to various anniversary years. The company, known for its expertise in diamonds, gems, and watches, provides this information to assist individuals in making thoughtful selections that honor personal achievements.

    The resource outlines traditional and modern gift associations alongside corresponding gemstones for each anniversary. For the first year, gold jewelry aligns with the traditional paper theme and modern clocks. The second year features garnet with cotton and china. Pearls accompany leather and crystal or glass for the third. Blue topaz corresponds to fruit or flowers and appliances in the fourth. Sapphire pairs with wood and silverware for the fifth. Amethyst relates to candy, iron, and wood in the sixth. Onyx connects to wool or copper and desk sets for the seventh. Tourmaline matches bronze or pottery and linens or lace in the eighth. Lapis aligns with pottery or willow, and leather for the ninth. Diamonds feature prominently with tin or aluminum in the tenth.

    Continuing the progression, turquoise accompanies steel and fashion jewelry for the eleventh year. Jade pairs with silk or linen and pearls in the twelfth. Citrine corresponds to lace and textiles or furs for the thirteenth. Opal relates to ivory and gold jewelry in the fourteenth century. Ruby aligns with crystal and watches for the fifteenth. Peridot connects to China and platinum in the twentieth century. Silver marks the twenty-fifth with silver in both traditional and modern categories. Pearls feature in the thirtieth alongside diamonds. Emerald pairs with coral and jade in the thirty-fifth. Ruby dominates the fortieth in both categories. Sapphire appears for the forty-fifth. Gold signifies the fiftieth with the golden jubilee. Alexandrite accompanies emerald for the fifty-fifth. Diamonds conclude with the sixtieth and diamond jubilee.

    This structured approach reflects the company’s commitment to educating customers on meaningful traditions. As a jewelry store in Fresno, CA, Ara Karkazian Watch & Jewelry Company integrates this knowledge into its offerings, ensuring selections resonate with personal stories. The guidance extends beyond anniversaries to encompass other occasions where jewelry serves as a lasting token.

    Ara Karkazian, co-owner and certified master watchmaker, noted the timeless appeal of such gifts. “Selecting a piece that aligns with anniversary traditions allows individuals to create lasting memories through items that endure over time,” said Ara Karkazian. His background in watchmaking, including graduation from the Watchmakers of Switzerland Training and Educational Program, informs the company’s approach to combining functionality with sentiment.

    Lena Karkazian, co-owner with 30 years in the jewelry business, emphasized the personalization aspect. “Custom designs enable customers to incorporate specific gemstones or styles that reflect their unique journeys, turning standard gifts into cherished heirlooms,” said Lena Karkazian. She handles bespoke creations and pearl stringing on site, contributing to the company’s reputation for distinctive pieces.

    In addition to gift guidance, the company maintains a state-of-the-art workshop for repairs and restorations. Master watchmakers handle everything from battery replacements to complete overhauls, serving both local and mail-in clients. The pre-owned watch department features brands such as Rolex, Patek Philippe, and Cartier, all restored with a five-year guarantee on functionality. Jewelry services include custom designs, laser inscription, and appraisals, supported by memberships in organizations like the American Watchmakers and Clockmakers Institute, Jewelers of America, and the Gemological Institute of America.

    The company’s history dates back to 1978 as a modest watch repair business. Ara Karkazian purchased it in 1990 from his brother George, having worked there since his teenage years. Together with Lena Karkazian, they expanded the showroom multiple times, creating a 3,000-square-foot boutique in northwest Fresno. This growth established it as the Central Valley’s engagement ring headquarters, with an extensive selection of bridal jewelry, loose diamonds, and fashion pieces.

    Community involvement remains a core element, with participation in local non-profit activities. The family-owned operation combines over 70 years of experience between Ara and Lena Karkazian, alongside master watchmaker Zohrab Megerdichian. This team ensures a comfortable, non-pressure environment for customers seeking engagement rings, anniversary bands, or corporate gifts from brands like Citizen and Baume & Mercier.

    Customer feedback underscores the company’s dedication. Individuals praise the knowledgeable staff, efficient repairs, and high-quality selection. One testimonial highlights the loyalty earned through consistent service, even from former residents who continue to send items for maintenance.

    Ara Karkazian Watch & Jewelry Company operates as a premier resource for jewelry and watches in the region. It specializes in sourcing fine brands and unusual pieces while offering expert services. The focus remains on building trust through impeccable service, from initial consultations to after-sales support. This approach positions the company as a trusted partner in commemorating life’s happiest moments.

    ###

    For more information about Ara Karkazian Watch & Jewelry, contact the company here:

    Ara Karkazian Watch & Jewelry
    Ara Karkazian
    (559) 780-8448
    arakarkazianwatchjewelry@gmail.com
    1776 W Bullard Ave, Fresno, CA 93711

  • Three Trillion-Dollar Frontiers, One Technology: How SMX Is Everywhere at Once

    Three Trillion-Dollar Frontiers, One Technology: How SMX Is Everywhere at Once

    NEW YORK, NY / ACCESS Newswire / December 5, 2025 / The market tends to categorize companies by the sector in which they operate. Gold companies go in one box. ESG infrastructure goes in another. Digital assets get their own lane entirely. That framework works for most organizations because most organizations only solve one problem at a time. SMX (NASDAQ:SMX) never fit that model. The company built a molecular identity platform designed to operate across industries that, on the surface, look unrelated. Gold provenance. Sustainability verification. Digital-asset creation through the Plastic Cycle Token. Three massive arenas, all moving in different directions, yet all beginning to align around the same technological foundation SMX has spent years refining.

    What makes this moment stand out is the speed at which these sectors are experiencing the same pressure point. The gold market is modernizing its authentication standards. ESG frameworks are tightening their requirements for measurable recovery. Digital-asset infrastructure is demanding real-world data instead of estimates. These are not parallel evolutions. They are symptoms of a global system running out of patience with unverifiable information. That is where SMX’s platform suddenly becomes the common denominator.

    It is not a gold technology, a sustainability technology, or a digital token system. It is an identity engine that assigns a molecular signature to materials and preserves it through any transformation. One capability, three massive markets, all converging at once.

    Interest is Broad, and Expanding Still
    In the gold sector, the impact is already visible. When precious metals move through global trading hubs, they lose track of their origins the moment they’re melted or recast. SMX broke that barrier. Its system allows gold to carry a persistent identity that survives the entire refining lifecycle. That single breakthrough changes how authenticity is verified, how supply chains are audited, and how trading hubs align with emerging integrity standards. It allows the metals world to move past subjective trust and into scientific certainty. And the same technology powering that shift is simultaneously being deployed far beyond bullion.

    Sustainability markets have long struggled with accuracy. Brands commit to recycled content targets. Regulators mandate circularity. Auditors request documentation. But none of it mattered if the material itself couldn’t prove its history. SMX entered that gap and brought molecular traceability to plastics, textiles, chemicals, and packaging. Materials that used to become anonymous the moment they were processed now retain identity from origin to recovery. That gives regulators harder evidence. It gives brands measurable performance. It gives recycling ecosystems a verification layer that eliminates uncertainty. ESG shifts from reporting to recording. And the very system enabling that shift is the same one redefining gold provenance.

    Digital assets are undergoing their own reckoning. Markets want tokens tied to actual, verifiable activity instead of speculative value. SMX made that possible with the Plastic Cycle Token. The PCT is not a financial instrument built on sentiment. It is a digital asset built on authenticated material performance captured by SMX’s molecular identity system. When verified recovery events occur, they are expressed digitally through the PCT, creating a market signal anchored to real behavior. That connection between physical proof and digital value is something the broader sector has been chasing for a decade. SMX delivered it because the same infrastructure supporting gold and ESG verification seamlessly extends into digital markets.

    A Convergence of Impact
    The real story here is not that SMX participates in three sectors. It is that these sectors are beginning to operate like different expressions of the same system. Gold demands proof of origin. ESG demands proof of impact. Digital assets demand proof of performance. SMX built proof at the molecular level, and that capability scales horizontally across all three arenas without redesign, repositioning, or dilution of purpose. The markets are simply catching up to the fact that the same underlying technology is solving the problems they thought were unrelated.

    This is the strategic inflection point. Not one market waking up, but three. Not a pivot, but a convergence. SMX is executing in gold, ESG, and digital assets simultaneously because the world is beginning to reorganize around a single requirement. Proof carried by the material itself. That is the engine SMX built. And that is why all three frontiers, and interest in the company, are accelerating at once.

    About SMX
    As global businesses face new and complex challenges relating to carbon neutrality and meeting new governmental and regional regulations and standards, SMX is able to offer players along the value chain access to its marking, tracking, measuring and digital platform technology to transition more successfully to a low-carbon economy.

    Forward-Looking Statements
    The information in this press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, statements regarding expectations, hopes, beliefs, intentions or strategies regarding the future. In addition, any statements that refer to projections, forecasts or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. The words “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “forecast,” “intends,” “may,” “will,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. Forward-looking statements in this press release may include, for example: successful launch and implementation of SMX’s joint projects with manufacturers and other supply chain participants of steel, rubber, plastic and other materials; changes in SMX’s strategy, future operations, financial position, estimated revenues and losses, projected costs, prospects and plans; SMX’s ability to develop and launch new products and services, including its planned Plastic Cycle Token; SMX’s ability to successfully and efficiently integrate future expansion plans and opportunities; SMX’s ability to grow its business in a cost-effective manner; SMX’s product development timeline and estimated research and development costs; the implementation, market acceptance and success of SMX’s business model; developments and projections relating to SMX’s competitors and industry; and SMX’s approach and goals with respect to technology. These forward-looking statements are based on information available as of the date of this press release, and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties. Accordingly, forward-looking statements should not be relied upon as representing views as of any subsequent date, and no obligation is undertaken to update forward-looking statements to reflect events or circumstances after the date they were made, whether as a result of new information, future events or otherwise, except as may be required under applicable securities laws. As a result of a number of known and unknown risks and uncertainties, actual results or performance may be materially different from those expressed or implied by these forward-looking statements. Some factors that could cause actual results to differ include: the ability to maintain the listing of the Company’s shares on Nasdaq; changes in applicable laws or regulations; the ability to implement business plans, forecasts, and other expectations, and identify and realize additional opportunities; the risk of downturns and the possibility of rapid change in the highly competitive industry in which SMX operates; the risk that SMX and its current and future collaborators are unable to successfully develop and commercialize SMX’s products or services, or experience significant delays in doing so; the risk that the Company may never achieve or sustain profitability; the risk that the Company will need to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; the risk that the Company experiences difficulties in managing its growth and expanding operations; the risk that third-party suppliers and manufacturers are not able to fully and timely meet their obligations; the risk that SMX is unable to secure or protect its intellectual property; the possibility that SMX may be adversely affected by other economic, business, and/or competitive factors; and other risks and uncertainties described in SMX’s filings from time to time with the Securities and Exchange Commission.

    EMAIL: info@securitymattersltd.com

    SOURCE: SMX (Security Matters) Public Limited

    View the original press release on ACCESS Newswire

  • XCF Global Moves to Double SAF Production with New Rise Reno Expansion

    XCF Global Moves to Double SAF Production with New Rise Reno Expansion

    • Initial development completed at New Rise Reno 2, advancing XCF’s second SAF production facility and positioning construction to begin in 2026.

    • $300 million planned investment will double XCF’s total SAF production capacity to ~80 million gallons annually, positioning New Rise Reno as a major U.S. SAF production center.

    • Global demand accelerates as mandates tighten, creating one of the strongest growth opportunities in renewable fuels – one that XCF’s modular SAF platform is positioned to capture.

    HOUSTON, TX / ACCESS Newswire / December 5, 2025 / XCF Global, Inc. (“XCF”) (Nasdaq:SAFX), a key player in decarbonizing the aviation industry through Sustainable Aviation Fuel (“SAF”), today announced new development milestones at its New Rise Reno 2 site, the Company’s second SAF production facility and the next deployment of its scalable, modular production platform.

    XCF has completed initial site work at New Rise Reno 2, including grading of the 10-acre parcel and construction of new access roads. Engineering, design, and project planning are underway, positioning construction to begin in 2026.

    Located adjacent to the existing New Rise Reno facility in Nevada, the new site will benefit from integration with common facilities such as gas, water, rail, and personnel offices as well as existing pre-treatment, hydrogen production, and broader logistics infrastructure – reducing capital costs, lowering execution risk, and accelerating time to production.

    Since inception, approximately $350 million has been invested in XCF’s flagship New Rise Reno facility. New Rise Reno 2 represents the next phase of this growth strategy, with an expected $300 million investment enabling XCF to double SAF production capacity to ~80 million gallons annually.

    Chris Cooper, CEO of XCF Global, commented:

    New Rise Reno 2 is the next leap forward in our growth strategy. By adding a second, fully integrated facility, we’re turning New Rise Reno intoa major U.S. SAF production center and positioning XCF for sustained, long-term growth. This expansion exemplifies how XCF grows: intentionally, efficiently, and with a platform built to meet surging global demand.”

    Rendering of New Rise Reno 2

    Expanding Global Reach

    The development of New Rise Reno 2 strengthens XCF’s ability to meet rising SAF demand across the world’s most important aviation markets. In November, XCF signed a Memorandum of Understanding (“MOU”) with BGN INT US LLC (“BGN”), a global energy and commodities group, to jointly develop global distribution, marketing, and offtake frameworks across Europe, the Middle East, and other strategic markets.

    The partnership would connect XCF’s expanding production capacity with BGN’s global logistics and trading network, creating an integrated supply chain from feedstock to finished fuel.

    This strategic alignment comes as demand accelerates across major aviation markets.

    U.S. SAF Grand Challenge: Federal targets call for 3 billion gallons of SAF per year by 2030 and 35 billion gallons to satisfy 100% of domestic demand by 2050; however, current U.S. production remains below 1% of jet fuel demand.

    ReFuelEU Aviation Mandates: Airlines will be required to blend 2% SAF in 2025, increasing to 6% by 2030, and 20% by 2035, ultimately rising to 70% by 2050. With regional supply unable to meet these mandated volumes, Europe is expected to face structural shortages and persistently elevated SAF pricing.

    Together, the U.S. and Europe represent one of the largest and fastest-growing opportunities in the clean-energy transition, with the U.S. SAF market projected to reach nearly $7 billion by 2030 and global demand exceeding $25 billion. XCF’s scalable, modular SAF platform is built to scale directly into this opportunity.

    XCF will continue to provide updates as development progresses.

    About XCF Global, Inc.

    XCF Global, Inc. (“XCF”) is a pioneering sustainable aviation fuel company dedicated to accelerating the aviation industry’s transition to net-zero emissions. Our flagship facility, New Rise Reno, has a nameplate production capacity of 38 million gallons per year, positioning XCF as an early mover among large-scale SAF producers in North America. XCF is advancing a pipeline of three additional sites in Nevada, North Carolina, and Florida, and is building partnerships across the energy and transportation sectors to scale SAF globally. XCF is listed on the Nasdaq Capital Market and trades under the ticker, SAFX. Current outstanding shares: ~208.3 million; <20% free float (as of December 5, 2025).

    To learn more, visit www.xcf.global.

    Contacts

    XCF Global:
    C/O Camarco
    XCFGlobal@camarco.co.uk

    Media:

    Camarco

    Andrew Archer | Rosie Driscoll | Violet Wilson

    XCFGlobal@camarco.co.uk

    Forward-Looking Statements

    This Press Release includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. In some cases, you can identify forward-looking statements by terminology such as “may”, “should”, “expect”, “intend”, “will”, “estimate”, “anticipate”, “believe”, “predict”, “potential” or “continue”, or the negatives of these terms or variations of them or similar terminology. These forward-looking statements, including, without limitation, statements regarding XCF Global’s expectations with respect to future performance and anticipated financial impacts of the recently completed business combination with Focus Impact BH3 Acquisition Company (the “Business Combination”), estimates and forecasts of other financial and performance metrics, and projections of market opportunity and market share, are subject to risks and uncertainties, which could cause actual results to differ materially from those expressed or implied by such forward-looking statements. These forward-looking statements are based upon estimates and assumptions that, while considered reasonable by XCF Global and its management, are inherently uncertain and subject to material change. These forward-looking statements are provided for illustrative purposes only and are not intended to serve as and must not be relied on by any investor as, a guarantee, an assurance, a prediction or a definitive statement of fact or probability. New risks and uncertainties may emerge from time to time, and it is not possible to predict all risks and uncertainties. Factors that may cause actual results to differ materially from current expectations include, but are not limited to: (1) changes in domestic and foreign business, market, financial, political, and legal conditions; (2) unexpected increases in XCF Global’s expenses, including manufacturing and operating expenses and interest expenses, as a result of potential inflationary pressures, changes in interest rates and other factors; (3) the occurrence of any event, change or other circumstances that could give rise to the termination of negotiations and any agreements with regard to XCF Global’s offtake arrangements; (4) the outcome of any legal proceedings that may be instituted against the parties to the Business Combination or others; (5) XCF Global’s ability to regain compliance with Nasdaq’s continued listing standards and thereafter continue to meet Nasdaq’s continued listing standards; (6) XCF Global’s ability to integrate the operations of New Rise and implement its business plan on its anticipated timeline; (7) XCF Global’s ability to raise financing to fund its operations and business plan and the terms of any such financing; (8) the New Rise Reno production facility’s ability to produce the anticipated quantities of SAF without interruption or material changes to the SAF production process; (9) the New Rise Reno production facility’s ability to produce renewable diesel in commercial quantities without interruption during the ongoing SAF ramp-up process; (10) XCF Global’s ability to resolve current disputes between its New Rise subsidiary and its landlord with respect to the ground lease for the New Rise Reno facility; (11) XCF Global’s ability to resolve current disputes between its New Rise subsidiary and its primary lender with respect to loans outstanding that were used in the development of the New Rise Reno facility; (12) payment of fees, expenses and other costs related to the completion of the Business Combination and the New Rise acquisitions; (13) the risk of disruption to the current plans and operations of XCF Global as a result of the consummation of the Business Combination; (14) XCF Global’s ability to recognize the anticipated benefits of the Business Combination and the New Rise acquisitions, which may be affected by, among other things, competition, the ability of XCF Global to grow and manage growth profitably, maintain relationships with customers and suppliers and retain its management and key employees; (15) changes in applicable laws or regulations; (16) risks related to extensive regulation, compliance obligations and rigorous enforcement by federal, state, and non-U.S. governmental authorities; (17) the possibility that XCF Global may be adversely affected by other economic, business, and/or competitive factors; (18) the availability of tax credits and other federal, state or local government support; (19) risks relating to XCF Global’s and New Rise’s key intellectual property rights, including the possible infringement of their intellectual property rights by third parties; (20) the risk that XCF Global’s reporting and compliance obligations as a publicly-traded company divert management resources from business operations; (21) LOIs and MOUs may not advance to definitive agreements or commercial deployment; (22) the effects of increased costs associated with operating as a public company; and (23) various factors beyond management’s control, including general economic conditions and other risks, uncertainties and factors set forth in XCF Global’s filings with the Securities and Exchange Commission (“SEC”), including the final proxy statement/prospectus relating to the Business Combination filed with the SEC on February 6, 2025, this Press Release and other filings XCF Global made or will make with the SEC in the future. If any of the risks actually occur, either alone or in combination with other events or circumstances, or XCF Global’s assumptions prove incorrect, actual results could differ materially from the results implied by these forward-looking statements. There may be additional risks that XCF Global does not presently know or that it currently believes are not material that could also cause actual results to differ from those contained in the forward-looking statements. In addition, forward-looking statements reflect XCF Global’s expectations, plans or forecasts of future events and views as of the date of this Press Release. These forward-looking statements should not be relied upon as representing XCF Global’s assessments as of any date subsequent to the date of this Press Release. Accordingly, undue reliance should not be placed upon the forward-looking statements. While XCF Global may elect to update these forward-looking statements at some point in the future, XCF Global specifically disclaims any obligation to do so.

    SOURCE: XCF Global, Inc.

    View the original press release on ACCESS Newswire

  • FittingPros Launches Industry’s First Data-Driven Golf Club Fitting Directory

    FittingPros Launches Industry’s First Data-Driven Golf Club Fitting Directory

    New platform solves the “discovery problem” in the golf equipment market, allowing golfers to compare over 370+ club fitters by technology, pricing, and brand availability.

    JACKSONVILLE, Fla., Dec. 4, 2025 / PRZen / Golf Datatech reports that nearly 80 percent of serious golfers have now been custom-fitted, and the demand for unbiased information has never been higher. However, fitting quality varies wildly from shop to shop.

    FittingPros helps golfers distinguish between a professional fitting studio and a quick retail cart fitting, ensuring they know exactly what they are getting before they book.

    FittingPros is the first centralized source of truth for the fitting market. Through the platform, golfers can search club fitters using data points that were previously difficult to find:

    • Location: Search fitters by name, city, and state, and drill down into their specific offerings, like fitters in Scottsdale that carry Titleist and Fujikura shafts.
    • Technology: Filter shops by specific launch monitors, including TrackMan, Foresight GCQuad, FlightScope, and other major systems.
    • Pricing: View upfront costs for each fitting service (Driver, Irons, Full Bag, etc.) directly on their profile.
    • Brand Availability: Locate fitters that carry specific club and shaft manufacturers, including Titleist, Callaway, Mizuno, TaylorMade, Ping, Cobra, Srixon, and more.
    • Fitter Type: Clearly distinguish between Independent studios, big-box retailers, and national chains.

    “Most golfers understand how fittings can help their game, but many don’t know where to start or all the local options available,” said Jon Livingston, founder of FittingPros. “Our goal is to make the search simple. Whether you’re a scratch player or a higher handicap golfer, you should be able to confidently find a golf club fitter equipped to help you play better.”

    FittingPros is expanding nationwide and has already populated listings for major golf hubs, including Florida, Georgia, South Carolina, Alabama, Texas, Arizona, and California.

    The platform also serves as a marketing tool for the industry. Every fitter can list their shop for free, with optional upgrades available for added visibility within their city and state.

    For more information or to search for a fitter in your area, visit https://fittingpros.com.

    About FittingPros
    FittingPros is a national online directory dedicated to connecting golfers with top-rated club fitting professionals. By providing detailed profiles that include pricing, technology, and brand inventory, FittingPros brings transparency to the custom equipment market, helping golfers of all skill levels play their best game.

    Press Release Distributed by PRLog

    Source: FittingPros

    Follow the full story here: https://przen.com/pr/33600076

  • Inside the Fight for Affordable Housing: Avery Headley Joins Terran Lamp for a Candid Bronx Leadership Conversation

    Inside the Fight for Affordable Housing: Avery Headley Joins Terran Lamp for a Candid Bronx Leadership Conversation

    In a new episode of The Terran Lamp Show, Executive Director Avery Headley discusses transforming Bronx buildings into stable, affordable homes, navigating complex housing challenges, and leading Beulah HDFC through a major preservation effort. His conversation with host Terran Lamp offers a rare, inside look at what real estate leadership demands today.

    BRONX, N.Y., Dec. 4, 2025 / PRZen / A new episode of The Terran Lamp Show features Executive Director Avery Headley in a detailed conversation about preserving affordable housing and stabilizing buildings across the South Bronx. The episode offers a clear look at how Beulah HDFC is addressing long-standing property challenges and strengthening operations for the families it serves.

    In the interview, Headley discusses his path from playing basketball overseas to leading a portfolio of 294 residential units and multiple commercial spaces. He explains how previously abandoned and deteriorated buildings were brought back into service and how the organization is managing major repair needs, regulatory requirements, and tenant engagement.

    “Preserving affordable housing is more than property management; it is about protecting families and maintaining the character of the community,” said Avery Headley, Executive Director of Beulah HDFC. “Every decision we make affects people’s stability, and that responsibility guides our approach.”

    Host Terran Lamp emphasizes the leadership behind the work. “Avery’s story is a strong example of community-centered leadership,” said Lamp. “His honesty about the challenges and opportunities within affordable housing gives listeners a perspective they rarely hear.”

    The episode provides practical insight into housing preservation, compliance, community partnerships, and the operational realities of managing legacy buildings. It offers listeners a clear understanding of the long-term strategies required to keep housing affordable in New York City.

    Listen to the episode on Apple Podcasts:
    https://podcasts.apple.com/us/podcast/the-terran-lamp-show/id1843246090?i=1000739200167

    Press Release Distributed by PRLog

    Source: Beulah HDFC

    Follow the full story here: https://przen.com/pr/33600144

  • America’s Most Festive Garages Wanted for Garage.com’s 2025 Holiday Contest

    America’s Most Festive Garages Wanted for Garage.com’s 2025 Holiday Contest

    Homeowners are invited to share their best holiday garage décor for a chance to win $500 and national recognition.

    ORLANDO, Fla., Dec. 3, 2025 / PRZen / Garage.com is inviting homeowners across the United States to bring their holiday spirit to the driveway with the launch of its Deck the Garage 2025 Contest, a national competition to find the most creative and festive holiday garage.

    Full contest details and entry information are available at https://garage.com/resources/deck-the-garage/

    The contest celebrates originality, curb appeal and community cheer. One lucky homeowner will win a $500 Visa gift card and be featured in a special holiday story on Garage.com.

    Key Dates

    • Entry Deadline: December 12, 2025
    • Voting: December 15–21, 2025 on Instagram (participants must vote for homes other than their own)
    • Winner Announced: December 23, 2025, on Garage.com and Instagram

    Quote

    “We see garages as more than just storage spaces—they’re part of the home,” said Abby Drexler, Digital PR Strategist at Garage.com. “This contest is a fun way to celebrate how people bring creativity, warmth, and holiday spirit to a space that often gets overlooked.”

    About Garage.com

    Garage.com is the go-to destination for garage inspiration, design ideas and homeowner insights. From renovation ROI guides to real-estate data reports, Garage.com helps homeowners make the most of one of their home’s most valuable spaces.
    Learn more at Garage.com or follow @garage.com_official on Instagram.

    Media Contact
    Abby Drexler
    abby@garage.com

    Press Release Distributed by PRLog

    Source: Garage.com

    Follow the full story here: https://przen.com/pr/33599927

  • SMX Didn’t Change Its Story; The World Finally Connected the Dots

    SMX Didn’t Change Its Story; The World Finally Connected the Dots

    NEW YORK, NY / ACCESS Newswire / December 5, 2025 / For most companies, visibility arrives when they reinvent themselves. SMX (NASDAQ:SMX) is the rare exception. It didn’t pivot. It didn’t rebrand. It didn’t sprint into the spotlight with a new campaign. It kept building the same core technology, the same infrastructure, and the same thesis it has carried since the beginning. What changed wasn’t SMX. What changed was the world’s ability to see the full picture.

    For years, the market tried to place SMX into a neat category. Some saw a sustainability company. Others saw a metals-traceability company. A different group saw a digital-asset data engine. Each interpretation was partially true but incomplete, because SMX never belonged to a single lane. It was always a platform company operating beneath multiple industries that were too disconnected from one another to notice they were solving the same problem. Then those industries began colliding, and the SMX story that once looked fragmented suddenly came into focus.

    Molecular Prints in Three Major Sectors
    Gold proved to be the first arena where that clarity surfaced. The sector had pushed authenticity as far as paperwork and refinery records could take it. But once gold loses its shape, it loses its story. SMX erased that limitation by embedding identity directly into the metal, giving it a memory that heat and pressure can’t delete. The bullion world realized it now had a path out of centuries of uncertainty. That was one dot on the map.

    Sustainability leaders uncovered another. ESG frameworks were tightening, regulations were hardening, and brands were running out of ways to prove recycled content with any degree of credibility. SMX’s molecular marking system stepped in as the missing verification layer. Plastics, textiles, chemicals, and industrial materials could now travel through the circular economy without losing their identity. What had been a reporting challenge became a measurement system. Another dot. Same technology.

    Digital ecosystems connected the third. Markets wanted assets tied to real-world performance, not speculation. SMX had already built the bridge. Its Plastic Cycle Token takes verified recovery events and expresses them digitally, using authenticated material data as the source. Suddenly, the same identity system that helped gold speak for itself and helped ESG claims become measurable became the backbone of a new category of digital signals. A third dot. Same system.

    What the world missed, until now, was that none of these dots were independent. They formed a pattern. Gold, ESG, and digital assets are not three distant markets. They are three sectors collapsing toward the same requirement: verifiable identity that survives transformation. SMX didn’t build three different solutions. It built one: a molecular identity platform flexible enough to live inside all three arenas without changing its core.

    Connecting the Dots
    Stakeholders across industries are connecting those dots faster than ever. Refiners see the same integrity engine that regulators see. Global brands see the same verification backbone that digital architects see. Institutions watching the metals world modernize see the same technology powering national circularity programs across Asia. The common thread is not what SMX says. It’s what the technology proves.

    That is why the narrative around SMX feels different now. Not because the company changed its trajectory, but because the world finally stopped evaluating it in isolation. SMX’s value doesn’t come from any single vertical. It comes from the way those verticals reinforce one another. Gold’s demand for authenticity strengthens ESG’s demand for transparency. ESG’s demand for transparency creates data that powers the PCT. The PCT creates a digital expression that circles back and elevates the entire platform.

    This is the moment where the disconnect disappears. The dots that once looked scattered now form a straight line pointing toward a unified system the market wasn’t ready to recognize, until the pressure across industries forced them to reevaluate what proof actually means.

    SMX didn’t change its story. It didn’t have to. The world simply learned how to read it.

    About SMX
    As global businesses face new and complex challenges relating to carbon neutrality and meeting new governmental and regional regulations and standards, SMX is able to offer players along the value chain access to its marking, tracking, measuring and digital platform technology to transition more successfully to a low-carbon economy.

    Forward-Looking Statements
    The information in this press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, statements regarding expectations, hopes, beliefs, intentions or strategies regarding the future. In addition, any statements that refer to projections, forecasts or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. The words “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “forecast,” “intends,” “may,” “will,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. Forward-looking statements in this press release may include, for example: successful launch and implementation of SMX’s joint projects with manufacturers and other supply chain participants of steel, rubber, plastic and other materials; changes in SMX’s strategy, future operations, financial position, estimated revenues and losses, projected costs, prospects and plans; SMX’s ability to develop and launch new products and services, including its planned Plastic Cycle Token; SMX’s ability to successfully and efficiently integrate future expansion plans and opportunities; SMX’s ability to grow its business in a cost-effective manner; SMX’s product development timeline and estimated research and development costs; the implementation, market acceptance and success of SMX’s business model; developments and projections relating to SMX’s competitors and industry; and SMX’s approach and goals with respect to technology. These forward-looking statements are based on information available as of the date of this press release, and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties. Accordingly, forward-looking statements should not be relied upon as representing views as of any subsequent date, and no obligation is undertaken to update forward-looking statements to reflect events or circumstances after the date they were made, whether as a result of new information, future events or otherwise, except as may be required under applicable securities laws. As a result of a number of known and unknown risks and uncertainties, actual results or performance may be materially different from those expressed or implied by these forward-looking statements. Some factors that could cause actual results to differ include: the ability to maintain the listing of the Company’s shares on Nasdaq; changes in applicable laws or regulations; the ability to implement business plans, forecasts, and other expectations, and identify and realize additional opportunities; the risk of downturns and the possibility of rapid change in the highly competitive industry in which SMX operates; the risk that SMX and its current and future collaborators are unable to successfully develop and commercialize SMX’s products or services, or experience significant delays in doing so; the risk that the Company may never achieve or sustain profitability; the risk that the Company will need to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; the risk that the Company experiences difficulties in managing its growth and expanding operations; the risk that third-party suppliers and manufacturers are not able to fully and timely meet their obligations; the risk that SMX is unable to secure or protect its intellectual property; the possibility that SMX may be adversely affected by other economic, business, and/or competitive factors; and other risks and uncertainties described in SMX’s filings from time to time with the Securities and Exchange Commission.

    EMAIL: info@securitymattersltd.com

    SOURCE: SMX (Security Matters) Public Limited

    View the original press release on ACCESS Newswire

  • Calidi Biotherapeutics and Nova Minerals Interviews to Air on the RedChip Small Stocks, Big Money(TM) Show on Bloomberg TV

    Calidi Biotherapeutics and Nova Minerals Interviews to Air on the RedChip Small Stocks, Big Money(TM) Show on Bloomberg TV

    ORLANDO, FLORIDA / ACCESS Newswire / December 5, 2025 / RedChip Companies will air interviews with Calidi Biotherapeutics, Inc. (NYSE American:CLDI) and Nova Minerals Limited (Nasdaq:NVA) on the RedChip Small Stocks, Big Money show, a sponsored program on Bloomberg TV this Saturday, December 6, at 7 p.m. Eastern Time (ET). Bloomberg TV is available in an estimated 73 million homes across the U.S.

    Access the interviews in their entirety at:

    In an exclusive interview, Eric Poma, Ph.D., CEO of Calidi, will appear on the RedChip Small Stocks Big Money show on Bloomberg TV to discuss Calidi’s pioneering approach to precision genetic medicine, enabled by its proprietary RedTail platform-an engineered, systemically delivered viral therapy designed to reach metastatic and difficult-to-treat tumors. The platform cloaks potent genetic payloads, such as IL-15 superagonist, within a human cell-derived envelope, allowing the virus to evade immune detection and find and specifically replicate in tumor cells at metastatic sites. With its scalable, non-integrating viral backbone and ability to deliver multiple genetic payloads, RedTail positions Calidi to address a vast oncology market projected to exceed $560 billion by 2033. The Company is advancing toward IND filing by the end of 2026. Calidi’s capital-efficient business model, strengthened balance sheet, and next-generation pipeline targeting both cancer and autoimmune diseases highlight the Company’s strong potential to deliver value to shareholders.

    Christopher Gerteisen, CEO of Nova Minerals, appears on the RedChip Small Stocks Big Money show on Bloomberg TV to outline the Company’s strategy to advance its Estelle Project in Alaska-one of North America’s largest undeveloped gold systems and a rapidly emerging U.S. critical minerals asset. Spanning 514 km² in the world-renowned Tintina Gold Belt, Estelle hosts a 35 km mineralized corridor with more than 20 gold and antimony prospects, including two defined multi-million-ounce gold resources and several drill-ready antimony targets with visible stibnite at surface. Gerteisen will highlight Nova’s dual-pronged development strategy: accelerating its path to becoming a tier-one gold producer while simultaneously establishing the first fully domestic, integrated U.S. antimony supply chain in decades-supported by a transformational US$43.4 million Defense Production Act Title III award from the U.S. Department of War. With military-grade antimony production targeted for 2026/27, active discussions underway with federal agencies and industrial partners, and a feasibility study progressing to expand the current 5.2-million-ounce gold resource, Nova is positioning itself as a strategically vital North American supplier at the intersection of critical minerals security and large-scale gold development.

    CLDI and NVA are clients of RedChip Companies. Please read our full disclosure at https://www.redchip.com/legal/disclosures.

    About Calidi Biotherapeutics

    Calidi Biotherapeutics (NYSE American: CLDI) is a clinical-stage immuno-oncology company pioneering the development of targeted therapies with the potential to deliver genetic medicines to distal sites of disease. The company’s proprietary Redtail platform features an engineered enveloped oncolytic virus designed for systemic delivery and targeting of metastatic sites. This advanced enveloped technology is intended to shield the virus from immune clearance, allowing virotherapy to effectively reach tumor sites, induce tumor lysis, and deliver potent gene therapies to metastatic locations.

    The lead candidate from the Redtail platform, currently in IND-enabling studies, targets non-small cell lung cancer, ovarian cancer, and other tumor types with high unmet medical need. Additionally, Calidi is developing protected virotherapies, in clinical-stage, for intratumoral and localized administration, focusing on a subset of injectable cancer indications.

    Calidi Biotherapeutics is headquartered in San Diego, California. For more information, please visit www.calidibio.com.

    About Nova Minerals Limited

    Nova Minerals Limited is a Gold, Antimony and Critical Minerals exploration and development company focused on advancing the Estelle Project, comprised of 514 km2 of State of Alaska mining claims, which contains multiple mining complexes across a 35 km long mineralized corridor of over 20 advanced Gold and Antimony prospects, including two already defined multi-million ounce resources, and several drill ready Antimony prospects with massive outcropping stibnite vein systems observed at surface. The 85% owned project is located 150 km northwest of Anchorage, Alaska, USA, in the prolific Tintina Gold Belt, a province which hosts a >220 million ounce (Moz) documented gold endowment and some of the world’s largest gold mines and discoveries, including Kinross Gold Corporation’s Fort Knox Gold Mine. The belt also hosts significant Antimony deposits and was a historical North American Antimony producer.

    Further discussion and analysis of the Estelle Project is available through the interactive Vrify 3D animations, presentations, and videos, all available on the Company’s website. www.novaminerals.com.au

    About RedChip Companies

    RedChip Companies, an Inc. 5000 company, is an international investor relations, media, and research firm focused on microcap and small-cap companies. Founded in 1992 as a small-cap research firm, RedChip gained early recognition for initiating coverage on emerging blue chip companies such as Apple, Starbucks, Daktronics, Winnebago, and Nike. Over the past 33 years, RedChip has evolved into a full-service investor relations and media firm, delivering concrete, measurable results for its clients, which have included U.S. Steel, Perfumania, Cidara Therapeutics, and Celsius Holdings, among others. Our newsletter, Small Stocks, Big Money, is delivered online weekly to 60,000 investors. RedChip has developed the most comprehensive service platform in the industry for microcap and small-cap companies. These services include the following: a worldwide distribution network for its stock research; retail and institutional roadshows in major U.S. cities; outbound marketing to stock brokers, RIAs, institutions, and family offices; a digital media investor relations platform that has generated millions of unique investor views; investor webinars and group calls; a television show, Small Stocks, Big Money, which airs weekly on Bloomberg US; TV commercials in local and national markets; corporate and product videos; website design; and traditional investor relation services, which include press release writing, development of investor presentations, quarterly conference call script writing, strategic consulting, capital raising, and more. RedChip also offers RedChat, a proprietary AI-powered chatbot that analyzes SEC filings and corporate disclosures for all Nasdaq and NYSE-listed companies, giving investors instant, on-demand insights.

    To learn more about RedChip’s products and services, please visit: https://www.redchip.com/corporate/investor_relations

    “Discovering Tomorrow’s Blue Chips Today”

    Follow RedChip on LinkedIn: https://www.linkedin.com/company/redchip/

    Follow RedChip on Facebook: https://www.facebook.com/RedChipCompanies

    Follow RedChip on Instagram: https://www.instagram.com/redchipcompanies/

    Follow RedChip on Twitter: https://twitter.com/RedChip

    Follow RedChip on YouTube: https://www.youtube.com/@redchip

    Follow RedChip on Rumble: https://rumble.com/c/c-3068340

    Subscribe to our Mailing List: https://www.redchip.com/newsletter/latest

    Contact:

    Dave Gentry
    RedChip Companies Inc.
    1-800-REDCHIP (733-2447)
    1-407-644-4256
    info@redchip.com

    –END–

    SOURCE: RedChip Companies, Inc.

    View the original press release on ACCESS Newswire

  • Revalia Bio Awarded Up To $26.7 Million ARPA-H Contract Award to Advance Drug Development with Human Data Trials

    Revalia Bio Awarded Up To $26.7 Million ARPA-H Contract Award to Advance Drug Development with Human Data Trials

    Funding backs a human-first approach to drug safety and efficacy, reducing reliance on animal testing and accelerating therapies for patients.

    NEW HAVEN, CT / ACCESS Newswire / December 5, 2025 / Revalia Bio (Revalia), developer of the Human Data Trial platform, today announced that they are serving as the technical lead for an up to $26.7M contract that they were awarded under the Advanced Research Projects Agency for Health (ARPA-H) Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST) program. The project, titled An Integrated Human Data Approach to Unlock the Future of In Silico Learning Models, supports Revalia’s mission to redefine how drug safety and efficacy are predicted before clinical trials.

    Revalia will lead the effort to build advanced AI-driven models trained on Human Data Trials, living systems derived from donated human organs, organ-on-chip platforms, and multimodal datasets. The goal is to reduce reliance on animal models and better predict how drugs behave in the human body, cutting costly late-stage failures and accelerating safer therapies.

    “This award is a turning point for Revalia and for the broader field of human-based trials,” said Greg Tietjen, PhD, CEO and Co-Founder of Revalia. “It’s a validation for us that confirms that the era for human data is here. Donated human organs are the Rosetta Stone of human-centered development, and our Human Data Trials platform transforms that gift into actionable insight for safer, more effective drugs. Most importantly, this program allows us to further deliver on our mission to honor the legacy of every donor by turning the loss of one life into knowledge that shapes the future of medicine.”

    A Human-First Alternative to Animal Models

    The ARPA-H CATALYST program is designed to accelerate safer, faster drug development by enabling more accurate predictions of safety and efficacy in investigational new drugs (INDs). CATALYST is led by ARPA-H Health Science Futures Mission Office Acting Deputy Director Andy Kilianski, Ph.D. Revalia’s integrated approach aligns with recent NIH and FDA initiatives to reduce reliance on animal testing by providing rigorous, clinically grounded human datasets to support regulatory innovation.

    “Drugs should be tested in the same biology, from the same patients, they are meant to treat,” said Janet Nikolovski, PhD, Chief Data and Innovation Officer at Revalia. “We are generating a unique, integrated human dataset encompassing everything from high level patient data to organ specific physiology and comprehensive molecular level analyses. These data will train models that we believe will better simulate clinical outcomes and reduce the risk of drug failure in clinical trials. This has the potential to change the paradigm for drug development, bringing better and faster therapies to patients who need them.”

    Collaborative Ecosystem: The Human Data Stack

    Revalia’s Human Data Trials platform forms the foundation of the company’s broader Human Data Stack, a framework that integrates donor organs, organoids, and organ-on-chip systems into a unified translational system. Revalia will collaborate with a national consortium that brings together:

    • A leading engineering research institute developing high-dimensional datasets through advanced platforms.

    • A regional nonprofit organization focused on expanding access to organ donation for scientific study.

    • An academic research lab specializing in artificial intelligence and machine learning to unlock predictive insights.

    • A top 10 pharma company looking to integrate New Approach Methodologies (NAMs) into their standard workflows to accelerate the pace of pre-clinical development

    “This project unites clinicians, biologists, engineers, and AI/ML experts to build advanced in silico models of human physiology that predict drug metabolism, pharmacokinetics, and toxicity,” said Nabil Boutagy, PhD, Director of Human Data Trial Operations at Revalia. “By integrating diverse expertise and generating multi-omic data at scale, we aim to cut drug development costs and timelines while guiding optimal dosing for patients.”

    ABOUT REVALIA BIO:

    Revalia Bio is transforming how new medicines are developed by offering on-demand access to real, functional human data. Built on decades of research in human organ perfusion, Revalia’s platform enables rigorous testing in donated human organs maintained under clinical conditions. This makes it possible to run Human Data Trials – studies that generate trial-quality data on safety, efficacy, and mechanism at any stage of development, before a molecule ever reaches a patient. For more information, visit www.revaliabio.com.

    MEDIA CONTACT:

    Nina Pfister, MAG PR at E: nina@mooringadvisorygroup.com; P: 781-929-5620

    SOURCE: Revalia Bio

    View the original press release on ACCESS Newswire