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ATLANTA, GEORGIA / ACCESS Newswire / November 13, 2025 / OMP, a leader in supply chain planning solutions, is showcasing how Kraft Heinz is transforming its global food supply chain at the Gartner Supply Chain Planning Summit 2025 in Denver. The leading food and beverage company will share how it is driving efficiency from farm to table with OMP’s Unison Planning™. By leveraging autonomous planning, decision intelligence, and AI optimization, Kraft Heinz enhances collaboration, manages complexity, and reduces waste.

Kraft Heinz’s journey to a smarter, more sustainable value chain

Thiago Serra, Head of Integrated Business Planning at Kraft Heinz, will discuss how smart, data-driven planning is helping the company build a more agile and sustainable value chain. Gain insights into how Kraft Heinz combines digital intelligence and end-to-end visibility to create real business impact across operations.

Explore human-AI synergy at the OMP booth

The Gartner Supply Chain Planning Summit, taking place December 2-3 in Denver, brings together global supply chain leaders to explore strategies for making high-impact, complex decisions and turning intelligence into execution.

OMP will be at booth 104 to showcase UnisonIQ, its game-changing AI orchestration framework. Embedded in the Unison Planning™ platform, it transforms supply chain decision-making through human-AI synergy. Visitors can experience firsthand how UnisonIQ is revolutionizing supply chain operations through always-on agents, the Unison Companion generative AI assistant, and advanced AI engines.

See how integrated planning, enhanced by the latest AI advancements, improves scenario modeling and empowers faster, smarter decisions – helping organizations strengthen resilience, overcome challenges, and achieve measurable business results.

Join OMP at Gartner to hear Kraft Heinz’s transformation journey firsthand and discover how Unison Planning™, driven by AI, can accelerate planning success and support your planning teams.

Session at a glance

Title: OMP: Real intelligence, real impact – Kraft Heinz’s journey to a smarter, more sustainable value chain
Speaker: Thiago Serra – Head of Integrated Business Planning at Kraft Heinz
When: Tuesday, December 2, 2025, 2:30 PM – 3:00 PM MST
Where: Gaylord Rockies Resort & Convention Center – 6700 N Gaylord Rockies Blvd, Aurora, CO 80019, United States

To see where you can meet OMP next, visit their events calendar here.

About OMP

OMP helps companies facing complex planning challenges to excel, grow, and thrive by offering the best digitized supply chain planning solution on the market. Hundreds of customers in a wide range of industries – spanning consumer goods, life sciences, chemicals, metals, paper, packaging, plastics – benefit from using OMP’s unique Unison Planning^™.

SOURCE: OMP

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A New Era of Kids Culinary Education Begins With First Pilot Location Opening in Clark, New Jersey, Spring 2026

CLARK, NJ / ACCESS Newswire / November 13, 2025 / CLARK, NJ – Little Kitchen Academy (LKA), the premier Montessori-inspired cooking academy for children and teens ages 3 to 18, announces a transformative multi-store licensing agreement with Whole Foods Market, the leading natural and organic foods retailer. LKA’s first East Coast location, Little Kitchen Academy Clark NJ, will launch inside Whole Foods Market located at the Clark Commons Shopping Center in Clark, New Jersey-one of the best places to live in NJ-opening Spring 2026, with plans for additional locations across North America.

At the heart of Little Kitchen Academy is a mission to empower children and teens with confidence, independence, and healthy habits that ripple out to families, schools, and entire communities. Little Kitchen Academy is creating a movement to bring meaningful, lasting change to the places it serves.

“Changing a child’s life can transform families, schools, and communities. Through our collaboration with Whole Foods Market, we’re expanding our Montessori-inspired culinary programs to more areas. We’re excited to open our first East Coast location in Clark and look forward to LKA’s positive impact on children, parents, educators, and neighbors. Together, we’re building a healthier, more confident future.” – Brian Curin, CEO/CMO & Co-Founder of Little Kitchen Academy

WHAT’S COMING TO CLARK, NJ AND THE GREATER REGION

• First East Coast pilot location, Little Kitchen Academy Clark NJ, opens Spring 2026.

• Signature 3-hour Montessori-inspired cooking classes and camps for ages 3-18 with caring instructors, small class sizes, and individual workstations, every child receives the time, tools, and attention they need to thrive.

• Healthy Habits for Life: From understanding where food comes from to making balanced meals.

• Toddler’s First Taste: cooking classes for 2-3-year-olds and their caregivers.

• Recipes inspired by Whole Foods Market ingredients.

• Appearances by Celebrity Chef Cat Cora.

• Community events and charitable initiatives supporting LKA’s Changing Lives From Scratch Fund and more.

• Plans for additional locations in Whole Foods Market stores across North America.

“Seeing Little Kitchen Academy reach the East Coast is a dream realized-a testament to the vision I had when we opened our very first LKA. From day one, I wanted to create a place where children could discover confidence, independence, and healthy habits that would ripple through their families, schools, and communities. Partnering with Whole Foods Market allows us to bring our Montessori-inspired programs to even more neighborhoods, empowering children, parents, educators, and neighbors to thrive together. This milestone isn’t just about expansion-it’s about fulfilling a promise to help every child build a healthier and more confident future, one delicious moment at a time.” – Felicity Curin, Founder/President & Chief Learning and Curriculum Officer.

WHY IT MATTERS

• A Revolution in Children’s Food and Culinary Education: Little Kitchen Academy has a vision for healthier, more empowered communities. With this expansion, we’re making it possible for every child and teen to discover the joy of cooking with fresh, wholesome ingredients-right in the heart of their neighborhood.

• Confidence, Independence, and Real-Life Skills: LKA’s hands-on programs don’t just teach recipes-they nurture independence, build confidence, and inspire lifelong healthy habits. Students leave each class proud, capable, and eager to share their new skills with family and friends.

• Together, we’ll celebrate local flavors, seasonal ingredients, and the power of coming together around food.

• Supporting Local Schools and Families: LKA is making transformative children’s culinary and food education more accessible to the entire community. We’re excited to collaborate with local schools, host community events, and create opportunities for every child to thrive.

• A Movement You Can Taste: This is more than an opening-it’s the start of a movement. The energy, excitement, and anticipation in Clark, NJ, and the greater NJ/NYC area are palpable. Families are ready. Schools are ready. The community is ready. We can’t wait to open our doors and change lives from scratch-one delicious moment at a time.

Stay Connected & Be First to Know!
Follow Little Kitchen Academy on social media and sign up for our newsletter at https://littlekitchenacademy.com/ to get exclusive behind-the-scenes updates, VIP event invitations, and the latest news on opening plans for LKA Clark NJ and future locations.

Be part of the movement-join us as we change lives from scratch for the whole community!

ABOUT LITTLE KITCHEN ACADEMY

Little Kitchen Academy is the premier Montessori-inspired cooking academy for children and teens, dedicated to changing lives from scratch. At LKA, students develop independence, confidence, and healthy eating habits that empower them to make informed choices and positively impact their communities. More than a cooking school, LKA is a movement to create a better world through responsible food education. LKA is proud to partner with leading brands including, BIRKENSTOCK, ChefWorks, ChopValue, Click & Grow, Emeco, IKEA, Küssi, PRISE Inc., Scrub Daddy, and Welcome Industries. The academy is guided by an esteemed group of special advisors: Celebrity Chef Cat Cora, Hollywood Legend Supermensch Shep Gordon, NBA Icon Russell Westbrook, and Hollywood Changemaker Oliver Trevena. In alignment with its mission to serve a brighter future, LKA supports impactful charitable organizations such as Changing Lives From Scratch Fund, Russell Westbrook Why Not? Foundation, Crisis Text Line, Kids Help Phone, and One Tree Planted.For a taste of LKA, visit littlekitchenacademy.com or join the LKA community on Facebook, Instagram, LinkedIn, and YouTube.

For media inquiries, please contact:

pr@littlekitchenacademy.com

SOURCE: Little Kitchen Academy

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District ranks first statewide on 2025 MCAS Science assessments, with nearly half of student population achieving top grade “exceeding expectations”

NORTH READING, MASSACHUSETTS / ACCESS Newswire / November 13, 2025 / Students in North Reading Public Schools achieved the highest science scores in Massachusetts on the 2025 Massachusetts Comprehensive Assessment System (MCAS) for elementary Science and Technology/Engineering.

The district ranked first among 319 public and charter districts statewide, with 92% of students meeting or exceeding proficiency expectations. This placed North Reading six points ahead of the next highest district. Nearly half of all students, 47%, achieved the top level of “Exceeds Expectations,”nine points higher than any other district in the state.

With proficiency rates reaching 95% in multiple cohorts, North Reading’s success represents a district-wide culture of excellence that ensures all students have access to high-quality science learning experiences.

“The dedication of our teachers and administrators, along with support from KnowAtom’s inquiry based curriculum, gives every student a chance to engage deeply with science,” said Sean Killeen, Assistant Superintendent for Teaching & Learning. “Our educators continue to engage students’ curiosity, hands-on learning, and make meaningful real-world connections which show in these results.”

For more than a decade, North Reading Public Schools have partnered with KnowAtom, a Massachusetts-based company and national provider of high-quality hands-on instructional materials, curriculum, and professional development for K-8 schools in NGSS adaptive and adoptive states, including Massachusetts’ STE Frameworks. This partnership equips teachers with research-based tools that help students think critically, conduct experiments, and reason like scientists and engineers to develop a lifelong understanding of key skills and concepts.

“When students apply what they learn through inquiry-based science instruction, they are encouraged to explore phenomena, ask meaningful questions, and uncover scientific concepts. Engaging in these inquiry-driven experiences enhances both their engagement and academic achievement.” , Grade 5 Teacher/Science Curriculum Leader – Batchelder School, Tina Borek.

Massachusetts consistently ranks among the top states in the nation for public education (Consumer Affairs, 2024). Within this highly competitive landscape, North Reading’s results stand out. While other leading districts such as Sudbury, Andover, Dover, and Brookline reported between 24% and 25% of students exceeding expectations, North Reading reached well above at 47% and maintained the highest overall proficiency rate.

“These results reflect what happens when teachers are trusted as professionals and equipped with effectively designed and appropriately supported resources. With KnowAtom, educators create classrooms where students take responsibility for their learning, think independently, and develop the habits of mind that drive achievement in science and beyond.,” said Francis Vigeant, CEO of KnowAtom. “We’re proud to support communities like North Reading that are creating learning environments where students think critically and learn more deeply than conventional, screen-first or textbook-only approaches typically allow.”

Contact Information

Nicole Lanoue
Press Contact
nlanoue@knowatom.com
617-475-3475 x2002

SOURCE: KnowAtom, LLC

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New to The Street will be covering across all media.

NEW YORK CITY, NY / ACCESS Newswire / November 13, 2025 / HPB, a German innovator in solid-state battery technology, has partnered with leading process engineering company Coperion to advance slurry production. This strategic collaboration integrates Coperion’s expertise in continuous processing with HPB’s battery technology with the potential to support future industrial-scale production readiness. HPB’s solid-state batteries offer significant improvements in safety, longevity, and environmental impact. With intellectual property protected in 96 countries, the technology provides up to 50% better environmental balance compared to conventional lithium-ion batteries.

Earlier this year, HPB and Coperion conducted joint tests at Coperion’s test facility in Stuttgart, Germany. Using their continuous extrusion systems, the teams examined whether HPB’s slurry parameters could be effectively achieved. The first tests demonstrated that the target viscosity could be met, opening the door to further investigation.

“Our primary goal was to validate that our proprietary slurry can be produced reliably and consistently at industrial scale. The successful trials using Coperion’s state-of-the-art equipment have confirmed that scaling up our technology is both feasible and efficient,” explained Markus Stichnote, Head of Development at HPB.

Coperion brings extensive expertise in scaling innovative material processes from laboratory to industrial production. “We are delighted to support HPB in translating their innovative battery tech into scalable production. By applying our advanced continuous mixing solutions, we demonstrated that even novel battery formulations can be produced safely, efficiently, and at scale.” said Massimo Bernert, Teamleader Sales Europe from Coperion.

After the team successfully achieved target viscosity using the extruder in the first tests, they will consider scaling up trials in the next rounds, keeping in mind the possibility of industrial-scale production in the future. To follow progress and explore partnership opportunities, stakeholders from the battery manufacturing, renewable energy, and clean technology sectors are invited to connect directly with HPB and Coperion.

Press Contacts:

HPB
Ananya Borgohain
Head of Marketing & PR
Ananya.Borgohain@highperformancebattery.de

Coperion GmbH
Julia Conrad
Marketing Communications
Julia.conrad@coperion.com

SOURCE: New To The Street

View the original press release on ACCESS Newswire

Timed with a sharp acceleration in AI-data-center expansion, with more than $60B in new projects announced in the last 90 days.

BOCA RATON, FL / ACCESS Newswire / November 13, 2025 / Entero Therapeutics, Inc. (NASDAQ:ENTO) (“Entero” or the “Company”) today announced that its wholly owned subsidiary, Grid AI, is finalizing the establishment of a U.S.-based leadership team composed of highly accomplished executives from the energy, power, and technology sectors. This marks a significant step in Grid AI’s expansion into the rapidly growing U.S. market for AI-ready digital infrastructure and orchestration technology.

Entero expects to announce the appointment of a U.S.-based Chief Executive Officer and an Executive Chairman for Grid AI in the near term. The incoming executive team brings deep public-markets experience, including having grown and led a global, publicly traded company in the demand-response and energy-flexibility sector. Their leadership track record is directly aligned with Grid AI’s strategy to integrate AI orchestration, energy optimization, and digital infrastructure controls across major hyperscale and enterprise AI deployments.

Grid AI’s leadership expansion comes at a pivotal moment for the global compute industry. This week, AMD CEO Dr. Lisa Su projected that the data-center market will reach $1 trillion globally by 2030. Supporting that growth is expected to require more than 2,000 new data centers worldwide, each demanding intelligent control systems, AI-driven power orchestration, and real-time market optimization-capabilities core to the Grid AI platform.

With the addition of this experienced U.S.-based leadership team, Grid AI is positioning itself to build the operational depth, deployment capability, and public-markets governance rigor required for the next phase of hyperscale AI infrastructure development.

“More than $50 million has been invested since 2019 to build, test, and commercialize this revolutionary autonomous platform,” said Jason Sawyer, CEO of Entero. “Establishing a dedicated U.S. leadership team now gives us the product-market fit and execution muscle to accelerate our integration into the domestic AI infrastructure landscape and support large-scale AI-driven SaaS deployments.”

Grid AI will provide additional updates on leadership appointments and U.S. expansion initiatives in the coming weeks.

Grid AI’s U.S. expansion plans are aligned with Entero’s broader objective to capture value across the rapidly evolving intersection of artificial intelligence, energy systems, and digital infrastructure.

Investor & Media Contacts:

Entero Investor Relations:
investors@enterothera.com

SOURCE: Entero Therapeutics, Inc.

View the original press release on ACCESS Newswire

The platform replaces fragmented, manual workflows with an autonomous AI system that drafts, validates, and reviews SEC disclosures in real time.

CHICAGO, IL / ACCESS Newswire / November 13, 2025 / Greenshoe, the first AI-native platform built specifically to automate and improve U.S. Securities and Exchange Commission (SEC) disclosures, today announced that it has raised $3 million in seed funding, led by AIX Ventures, with participation from Hearst Level Up Ventures, Blueprint FTC, Service Provider Capital, and various strategic angels. The capital will fuel Greenshoe’s engineering and go-to-market expansion as the company launches its commercial platform for public company reporting.

On average, as an example, it takes about 180 hours just to prepare a 10-Q, at an expense that can range from roughly $50,000 for smaller companies to well over $1 million for large-cap enterprises, a costly, error-prone process filled with repetitive work, complexity, and risk. Greenshoe modernizes these complex workflows with an AI-native system that uses regulatory precedent, market norms, and real-time company data to deliver faster, more consistent, and compliance-grade disclosures.

“SEC filings are the foundation of market transparency, but the workflows powering them are stuck in a pre-AI world,” said Payton McCoy, CEO and co-founder of Greenshoe. “As a lawyer, I spent hundreds of hours manually preparing SEC disclosures, including 10-Ks, 8-Ks, and IPO filings. That said, Greenshoe is about more than just saving time. It’s about improving disclosure quality and making this work easier to do. We’re laying the rails for a smarter, faster capital markets ecosystem.”

Greenshoe handles niche, but critical workflows such as:

• Real-time compliance checks and validations

• Draft generation based on regulatory precedent and market comparables

• SEC comment analysis and response support

• Peer-based benchmarking and research

“We’re building the infrastructure layer for AI-native disclosure intelligence,” said Dr. Yi Zhang, CTO and co-founder. “Our deep-research agent fuses reasoning, evaluation, reflection, and human feedback into a continuous improvement loop. Every interaction sharpens the system, compounding domain expertise into an advantage that makes the platform more intelligent.”

Greenshoe’s architecture is built for complex document processing, combining agentic retrieval-augmented generation (RAG), domain-specific benchmarking, and structured reasoning over SEC disclosure requirements. Greenshoe conducts deep research on each filing and transforms that analysis into precise, context-aware drafting actions grounded in how disclosures evolve, how they compare to peers, and how they align with SEC expectations.

“SEC disclosures are among the most important and complex documents in corporate finance, and Greenshoe is the first team we’ve seen that truly understands both the regulatory nuance and the AI infrastructure required to modernize them,” said Jason McBride, Partner at AIX Ventures. “We invested because Greenshoe isn’t just building a tool. They’re defining an entirely new layer in the regulatory tech stack.”

Greenshoe was built for the roughly 4,700 public companies in the U.S. that face similar challenges navigating evolving SEC expectations, internal approvals, and market comparables. The platform is commercially available and already being adopted by legal teams and capital markets professionals. Early feedback indicates time savings of up to 90% for certain tasks. To learn more or request a demo, visit https://www.greenshoe.ai/.

ABOUT GREENSHOE:

Greenshoe is the first AI-native platform for SEC disclosure automation. Founded by former Kirkland & Ellis attorney Payton McCoy and and Yi Zhang, PhD, previously a Senior Applied Scientist at AWS AI, Greenshoe automates the research, drafting, benchmarking, and compliance review of public company filings. The company is on a mission to become the AI operating system for corporate disclosure, transforming compliance into an intelligent, real-time system that benefits issuers, investors, and regulators alike. Learn more at https://www.greenshoe.ai/.

MEDIA CONTACT:

Nina Pfister
MAG PR
nina@mooringadvisorygroup.com

SOURCE: Greenshoe

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MELBOURNE, FL / ACCESS Newswire / November 13, 2025 / Skymantics, LLC, an SBA 8(a)-certified small business, offers a full-spectrum Artificial Intelligence (AI) services for state and local governments. Moving beyond a single product, Skymantics is offering a comprehensive suite of AI solutions-from strategic planning and ethical-use consulting to AI-powered automation and predictive optimization-all built on a proven foundation of federal-grade data security.

While many agencies are exploring generative AI, Skymantics delivers the full lifecycle of AI services required for mission-critical operations:

• AI Strategy and Readiness: We begin with readiness assessments that evaluate an agency’s data, infrastructure, and staff to define clear business goals and measurable KPIs.

• AI-Powered Automation: We use Unsupervised Machine Learning to automate complex, manual workflows. Our DAISY platform, for example, automates the analysis of complex data logs to detect anomalies and flag deviations, turning a slow review process into an efficient, exception-based workflow.

• Predictive Planning & Optimization: We employ advanced techniques like Reinforcement Learning to help agencies optimize complex resource allocation. Our Collaborative AI Forestry Planner for Natural Resources Canada allows stakeholders to model and compare “what-if” scenarios for multi-year land use, balancing competing goals like revenue and sustainability.

• Privacy-Safe Synthetic Data: Our flagship DataGenesis platform creates “Synthetic Digital Twins”-statistically accurate, artificial models of populations and infrastructure. This enables “what-if” planning for disaster response, transportation, and public health without ever exposing sensitive citizen PII or PHI.

This comprehensive approach is proven at the highest levels of government. As the prime contractor for the Internal Revenue Service’s (IRS) Simulation of the Nation (SimoN) engine , Skymantics built an AI-driven platform that not only generates high-fidelity synthetic taxpayer data to protect privacy but also models complex fraud and non-compliance scenarios. This project demonstrates our unique ability to handle enterprise-scale AI, stringent security, and complex business logic simultaneously.

“Our experience with the Department of the Treasury/IRS and Department of Transportation/FAA shows that the biggest hurdle for government AI isn’t just the technology-it’s trust and a clear path to measurable results,” said Charles Chen, CEO. “We’re not just offering a single tool; we’re offering a complete AI adoption framework that prioritizes security, ethics, and mission outcomes from day one.”

About Skymantics

Skymantics, LLC is an SBA 8(a)-certified small business dedicated to modernizing the nation’s most critical government systems. We specialize in providing AI, data, and geospatial solutions to government, healthcare, and financial industries, leveraging the power of data for transformative solutions.

Contact::

Antonio Correas
+1 202 780 7591
antonio.correas@skymantics.com

SOURCE: Skymantics, LLC

View the original press release on ACCESS Newswire

GREENVILLE, SOUTH CAROLINA / ACCESS Newswire / November 13, 2025 / Cameron Ashley Building Products (Cameron Ashley) has opened a new distribution center in Jacksonville, Florida, strengthening its service capabilities across North Florida and Georgia’s coastal markets.

This strategic expansion gives customers faster, more reliable access to a full suite of residential and light commercial building products, helping them keep projects on schedule and customers satisfied.

The Jacksonville facility is a core market location, stocking Roofing, Gypsum, Insulation, and all related accessories. Cameron Ashley delivers convenience, speed, and local expertise to meet growing demand in one of the Southeast’s fastest-growing construction markets.

“This new Jacksonville facility enhances our statewide network, allowing us to deliver faster and more reliably across Florida,” said John Gambone, Regional Vice President. “By stocking our Core 3 products, we’re giving customers the tools they need to compete and win – backed by same-day or next-day delivery and the product knowledge and service they expect from Cameron Ashley.”

The new facility will be led by Distribution Center Manager Mark Mixon, a veteran professional in the roofing and insulation industries. “With years of experience supporting customers in this region, I understand their challenges,” said Mixon. “Our Jacksonville team knows the products, knows the market, and is ready to deliver the fast, dependable service customers deserve.”

With Jacksonville now online, Cameron Ashley operates a growing network of Florida distribution centers in Lakeland, Fort Pierce, and Fort Myers, ensuring statewide coverage and next-day delivery to nearly every major metro area.

The Jacksonville Distribution Center is located at 2210 Melson Avenue, Suite 101, Jacksonville, FL 32254, and can be reached at 904-807-2919.

About Cameron Ashley Building Products, Inc.

Cameron Ashley is a leading wholesale distributor of roofing, insulation, gypsum, siding, and other specialty building products. We deliver a premier portfolio of nationally recognized brands to customers across the lumber and building materials industry.

With more than 70 distribution centers nationwide, we stock large volumes of building products locally and offer flexible, customer-centric delivery options through our F^ST same-day or next-day delivery platforms.

Our relationship-driven approach includes the industry-leading PLUS® Points loyalty program, free merchandising support, as well as exclusive purchasing and show incentives. Customers can shop anytime through either our CONNECT online portal or mobile app, which provide real-time access to product availability, pricing, order history, secure payments, and detailed product specs and warranties.

To learn more or place an order, visit cameronashleybp.com.

SOURCE: Cameron Ashley Building Products

View the original press release on ACCESS Newswire

Crofelemer can potentially extend and save lives of microvillus inclusion disease patients, reducing the volume of the total parenteral support (PS) necessary for them to survive

Groundbreaking PS reduction of up to 37% is unprecedented; No approved treatments exist for MVID

SAN FRANCISCO, CA / ACCESS Newswire / November 13, 2025 / Jaguar Health, Inc. (NASDAQ:JAGX) (Jaguar) family company Napo Pharmaceuticals (Napo) today provided a recap of the November 8, 2025 presentation at the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) Annual Meeting describing the initial groundbreaking results of an independent investigator-initiated trial (IIT) of crofelemer in the UAE for treatment of pediatric intestinal failure, which includes patients with ‘intestinal failure’ due to microvillus inclusion disease (MVID) and short bowel syndrome (SBS-IF).

“The intestines of patients with the ultrarare genetic disorder MVID do not function properly, as is often the case with patients having intestinal failure due to short bowel syndrome. The intestines of these patients are unable to absorb the fluids, electrolytes and nutrients required to survive and thrive. Intestinal failure is a debilitating, lifelong condition that often requires patients to receive life-sustaining fluids, electrolytes and nutrients through intravenous administration, which consists of total parenteral nutrition (TPN) with supplemental intravenous fluids, which together constitute parenteral support (PS). Most intestinal failure patients require PS up to 7 days a week, and sometimes for 20 hours or more per day,” said Lisa Conte, Jaguar’s founder, president, and CEO.

While crucial for these patients, total parenteral support is associated with significant toxicities to patients, similar to some toxicities associated with chemotherapy, often causing serious health problems including infections, metabolic complications, liver and kidney function problems – as well as a risk of neurodevelopmental delay. These symptoms may emerge at any time in intestinal failure patients, and often become life-threatening.

As presented at NASPGHAN, the results of this ongoing and independent proof-of-concept trial of crofelemer demonstrate disease progression modification through reduction of total parenteral support (PS) in pediatric intestinal failure patients that ranged from 12 to 37%. Specifically, in the two SBS-IF patients who have completed treatment, the results show crofelemer reduced PS between 12.5 to 15.6% at the highest dose over the 12-week treatment period, together with reduced loose watery stools frequency. For the initial MVID patient who has completed treatment, PS needs were reduced by up to 27% at the highest dose over the initial 12-week treatment period and up to 37% during the extension period upon reinitiation of crofelemer treatment, and also showed reduced frequency of loose watery stools. These findings support continued evaluation of crofelemer to reduce PS needs for pediatric intestinal failure patients.

The presentation on November 8, 2025 at NASPGHAN, was titled Exploratory Single-Arm, Open-Label Non-Randomized Trial Evaluating the Safety and Effectiveness of Crofelemer in Pediatric Patients with Intestinal Failure. The study’s primary investigator, Dr. Mohamad Miqdady, Division Chief of the Pediatric Gastroenterology, Hepatology & Nutrition Division at Sheikh Khalifa Medical City (SKMC), a tertiary care center in Abu Dhabi in the UAE, described these initial findings in pediatric intestinal failure patients with crofelemer treatment.

A recognized leader in pediatric gastroenterology, Dr. Miqdady is Professor of Pediatric Gastroenterology at Khalifa University’s medical school, and completed his Fellowship in Pediatric Gastroenterology at Baylor College of Medicine and Texas Children’s Hospital in Houston. He is a member of Napo’s Scientific Advisory Board.

MVID is a devastating ultrarare pediatric disorder, with an estimated worldwide prevalence of 100-200 patients, characterized by severe malabsorption that requires life-sustaining parenteral support to meet the nutritional, fluid and electrolyte requirements of the child, and for which there are currently no approved treatments. MVID has a lethal natural history along with significant co-morbidities. Short bowel syndrome (SBS) affects approximately 10,000 to 20,000 people in the U.S., according to the Crohn’s & Colitis Foundation, and it is estimated that the population of SBS patients in Europe is approximately the same size.

In addition to supporting the IIT in the UAE, Napo is also conducting the placebo-controlled clinical trial of crofelemer in pediatric MVID patients at sites in the U.S., E.U., and Middle East under appropriate regulatory approvals in each of these geographies. The company is also providing crofelemer powder for oral solution for use in two expanded access programs in intestinal failure patients the U.S. to treat adult and pediatric intestinal failure patients with short bowel syndrome and MVID, respectively.

The mission of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) is to be a world leader in research, education, clinical practice and advocacy for pediatric gastroenterology, hepatology and nutrition in health and disease. NASPGHAN strives to improve the care of infants, children and adolescents with digestive disorders by promoting advances in clinical care, research and education.

About the Jaguar Health Family of Companies

Jaguar Health, Inc. (Jaguar) is a commercial stage pharmaceuticals company focused on developing novel proprietary prescription medicines sustainably derived from plants from rainforest areas for people and animals with gastrointestinal distress. Jaguar family companies Napo Pharmaceuticals (Napo) and Napo Therapeutics S.p.A. focus on the development and commercialization of novel crofelemer powder for oral solution for the treatment of rare and orphan gastrointestinal disorders with intestinal failure, including microvillus inclusion disease and short bowel syndrome.

For more information about:

Jaguar Health, visit https://jaguar.health

Napo Pharmaceuticals, visit www.napopharma.com

Napo Therapeutics, visit napotherapeutics.com

Forward-Looking Statements

Certain statements in this press release constitute “forward-looking statements.” These include statements regarding Jaguar’s expectation that crofelemer can potentially extend and save lives of MVID patients, reducing the volume of the PS necessary for them to survive. In some cases, you can identify forward-looking statements by terms such as “may,” “will,” “should,” “expect,” “plan,” “aim,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential” or “continue” or the negative of these terms or other similar expressions. The forward-looking statements in this release are only predictions. Jaguar has based these forward-looking statements largely on its current expectations and projections about future events. These forward-looking statements speak only as of the date of this release and are subject to several risks, uncertainties, and assumptions, some of which cannot be predicted or quantified and some of which are beyond Jaguar’s control. Except as required by applicable law, Jaguar does not plan to publicly update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise.

Contact:

hello@jaguar.health
Jaguar-JAGX

SOURCE: Jaguar Health, Inc.

View the original press release on ACCESS Newswire

The annual list recognizes the leading B2B companies that have proven track records of supporting entrepreneurs and helping companies grow

CLEARWATER, FL / ACCESS Newswire / November 13, 2025 / AmeriLife, a national leader in life and health insurance distribution, wealth management, and retirement solutions, is proud to announce its recognition on the Inc. Power Partner Awards for the third consecutive year. The prestigious list honors B2B organizations that have proven track records of supporting entrepreneurs and helping startups grow. AmeriLife was recognized in the categories of General Excellence, Marketing Creativity & Branding, and Best United States Power Partner.

“This incredible recognition is a testament to our team’s continued dedication to supporting entrepreneurs and helping businesses thrive,” said Scott Perry, Chairman and CEO of AmeriLife. “We’re honored to be acknowledged for achievements that reflect our commitment to providing exceptional service and support to our affiliate partners.”

As a national leader in life and health insurance distribution, wealth management, and retirement solutions, AmeriLife’s partnership program has become a benchmark for independent and field marketing organizations seeking to expand their reach and resources without compromising operational control over their business. By partnering with AmeriLife, companies can leverage the firm’s extensive distribution network, advanced marketing capabilities, technology solutions, and regulatory compliance tools, allowing them to focus on their core business while driving growth.

AmeriLife’s recent strategic moves have further strengthened its market position. In March, AmeriLife finalized its acquisition Crump Life Insurance Services, enhancing its wealth distribution capabilities within the institutional, IMO, and BGA segments. Crump’s expertise spans life insurance and retirement products, and it partners with over 31,000 financial professionals to deliver holistic solutions. This acquisition marked a significant step forward for AmeriLife, transforming its wealth distribution approach and delivering comprehensive, integrated solutions.

AmeriLife, through its affiliate Saybrus Partners, also entered into a strategic partnership with SterlingBridge Insurance Agency, expanding its national reach and capabilities in life insurance and annuity distribution. This partnership demonstrates the ability for affiliates to access capital and M&A support to add key capabilities they need to drive growth. Specifically, this partnership brought best-in-class capabilities in back-office operations and institutional and independent distribution, complementing Saybrus Partners’ wholesaling and sales support model.

The success of AmeriLife’s affiliate partners is also noteworthy. Four of its affiliate partners were recognized on the 2025 Inc. 5000 list of the fastest-growing private companies in America, including Florida Financial Advisors, Hoffman Financial Group, Brookstone Capital Management, and Pinnacle Financial Services. This recognition underscores the exceptional growth and innovative spirit of these companies, which are integral to AmeriLife’s mission.

Companies on the Inc. Power Partner list received top marks from clients for being instrumental in helping leadership navigate the dynamic world of startups. These B2B partners support entrepreneurs across various business functions, including hiring, compliance, infrastructure development, cloud migration, fundraising, and more, allowing founders to focus on their core missions.

“The entrepreneurial journey and community are core to Inc.’s mission, and it’s a true honor to celebrate this year’s Inc. Power Partners — the companies dedicated to helping small businesses and entrepreneurs,” says Bonny Ghosh, editorial director at Inc. “Whether they’re coordinating complex marketing campaigns or reliably supporting the day-to-day infrastructure of growing companies, these honorees aren’t simply B2B providers — they are true partners in helping businesses grow and succeed.”

For more information or to view the complete list of honorees, visit Inc.com/Power-Partner-Awards.

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About AmeriLife

AmeriLife’s strength lies in its mission: to provide insurance and retirement solutions that help people live longer, healthier lives. AmeriLife develops, markets, and distributes life and health insurance, annuities, and retirement planning solutions to enhance the lives of pre-retirees and retirees across the United States. For over 50 years, AmeriLife has partnered with top insurance carriers to provide value and quality to customers through a national distribution network of over 300,000 agents, financial professionals, and more than 160 marketing organizations and insurance agencies. For more information, visit AmeriLife.com and follow AmeriLife on Facebook and LinkedIn.

About Inc.

Inc. is the leading media brand and playbook for entrepreneurs and business leaders shaping our future. Through journalism, Inc. aims to inform, educate, and elevate the profile of its community: the risk-takers, the innovators, and the ultra-driven go-getters who are creating the future of business. Inc. is published by Manseto Ventures, along with fellow leading business publication Fast Company. For more information, visit www.inc.com.

Contacts:

Media

Jeff Maldonado
AmeriLife
media@amerilife.com

Partnership Inquiries

Alex Hyer
AmeriLife
corporatedevelopment@amerilife.com

SOURCE: AmeriLife

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