Blog

Focused on advancing its strategy for sustainable, scalable expansion, the Company unveils its refreshed brand identity, outlines its integrated farm-to-shelf model and details its disciplined path for future growth.

VANCOUVER, BC AND BREDA, NETHERLANDS / ACCESS Newswire / December 2, 2025 / Organto Foods Inc. (“Organto” or “the Company”), (TSXV:OGO)(OTCQX:OGOFF)(FSE:OGF0), a leading provider of organic and fairtrade fruit and vegetable products, today announced key milestones underscoring its transformation into a stronger, more disciplined and growth-ready organization. Following a 21-month restructuring, the Company has streamlined operations and strengthened both its balance sheet and financial performance, positioning it for sustained, profitable expansion.

“Organto today is fundamentally sounder and better positioned for scalable growth,” said Steve Bromley, Chief Executive Officer & Co-Chair of Organto. “Over the past almost two years, we’ve repositioned and streamlined our business, strengthened our financial foundation and demonstrated our ability to grow both quickly and responsibly. With disciplined execution and a clear strategy, we’re advancing our integrated asset-efficient model, with plans to broaden our product portfolio and create long-term value for shareholders.”

Transformation Milestones and Momentum
Following a comprehensive 21-month restructuring, Organto has repositioned itself for scalable, sustainable growth:

• Strong performance: YTD Q3 2025 sales of $45.9M, up 222% year-over-year and cash operating costs as a percentage of sales reduced to 7.3% from 13.4% in the prior year, with adjusted EBITDA performance improvement year-over-year, realizing the Company’s first ever positive EBITDA quarter in Q1 2025.

• Integrated operations: Organto’s operations have been fully integrated, managing sourcing, logistics, quality control, certification and retail execution across key European markets.

• Asset-efficient model: Scalable supply chain connecting certified organic growers to leading retailers year-round, optimizing cost, speed, and sustainability across markets, and positioning for further optimization of digitally connected technologies.

• Strengthened balance sheet: Eliminated all convertible debt, improved liquidity, established new financing and foreign exchange facilities with a premier bank with deep roots in the agricultural and food sectors and established a leaner, greener and asset-efficient operating model.

• Expanded retail relationships: Serving a growing network of leading European grocers under branded, private-label, and direct-distribution programs with recurring annual commitments.

• Foundation for growth: Positioned to expand fresh product categories, evaluate market entry into North America and entry into adjacent value-added ingredient and consumer product segments.

A Refreshed Brand for a Reinvigorated Vision
To mark this new chapter the Company is today launching its modernized brand image – including an updated logo, visual system and digital presence. The move reflects the Company’s evolution into an integrated global ecosystem and aligns its visual identity with its operational structure and long-term vision, reinforcing its position as a trusted partner in transparent and responsible food systems.

The Company’s guiding principles, represented by the three symbolic leaves in its new logo, reflect the foundation of this ecosystem:

• Healthy: Providing nutritious, responsibly sourced foods that meet growing consumer demand.

• Value-Driven: Creating opportunity and shared value for growers, partners, customers, team members and shareholders.

• Sustainable: Embedding transparency, traceability, and ethical practices across every stage of its operations.

“These three principles guide what we do, from how we source and operate to how we work and grow with our partners,” added Steve Bromley. “They lead our actions with the goal of ensuring that as we scale, profitability and purpose stay aligned across our global network.”

An Integrated Global Ecosystem
At the heart of Organto’s renewed strategy is a clear purpose: to make healthy, sustainable foods reliably available through a responsible, connected global network.

Guided by this mission, Organto operates as an integrated ecosystem connecting sustainable growers, partners and retailers through an asset-efficient supply chain. By combining global sourcing, logistics and in-market retail execution, Organto transforms traditionally fragmented value chains into a coordinated farm-to-shelf system, delivering year-round availability, full traceability and scalable efficiency.

“Our integrated ecosystem connects key part of the supply chain – from grower to retailer – allowing us to minimize waste, improve efficiency and create shared value for each of our partners,” commented Steve Bromley. “Together, we are championing a smarter, more sustainable way to bring organic foods to the world.”

Built On Transparency, Trust, And Responsible Growth
Organto’s success is underpinned by a disciplined operating culture, strong governance, and a commitment to transparency at every level of its business.

• Governance and Leadership: Led by a seasoned management team with decades of experience in global food systems, finance, and organics, Organto is structured for accountability and performance. A streamlined governance model ensures clear oversight, data-driven decision-making and disciplined capital allocation.

• Product Integrity: Organto’s products meet rigorous global standards, including Organic, Fairtrade, Global G.A.P., and other certifications.

• Transparency and Traceability: Products are tracked from field to shelf through SKU-level audit trails, offering visibility into product origin, quality, and environmental impact.

• Sustainability Commitment: Organto embeds sustainability and ethical sourcing into its business model – supporting fairtrade practices and living wages across its growing regions. By minimizing waste, optimizing transport and embracing data-driven efficiencies, Organto aligns performance with environmental stewardship.

• Year-Round Supply and Scale: Through its “follow-the-sun” sourcing network and strategically located entry ports and distribution hubs, Organto targets to provide consistent year-round availability of high-demand categories.

• Established Customer Base: Organto serves a growing network of leading retail and distribution partners across Europe, including several of the continent’s largest grocery chains.

Positioned For Continued Growth
Backed by a lean, asset-efficient model and strong category expertise, Organto is well positioned to capitalize on accelerating demand for organic and fairtrade foods. The global organic food and beverage market is projected to reach around US $1 trillion by 2034¹, growing at a compound annual growth rate of 13.7% from 2025 to 2034¹, driven by increasing consumer awareness, retailer sustainability commitments and regulatory support for traceable food systems.

Even amid broader industry headwinds, including inflationary pressures, supply chain consolidation and tightening ESG standards, Organto’s integrated model delivers stability, visibility and scalability.

Organto’s refreshed brand and strengthened foundation mark a pivotal moment for the Company as it advances its strategy for sustainable, profitable growth. With a fortified balance sheet, scalable infrastructure and expanding retail relationships, Organto is advancing a disciplined strategy for sustainable growth – extending its leadership in Europe while evaluating opportunities in North America and adjacent value-added categories.

ON BEHALF OF THE BOARD
Steve Bromley
Chief Executive Officer & Co-Chair

Investor & Media Contact:
John Rathwell
SVP, Corporate Development
john.rathwell@organto.com
www.organto.com

¹ Precedence Research. Organic Food and Beverages Market Size, Growth, Trends, Report (2025-2034). Last updated Nov 6, 2025.

About Organto Foods
Organto Foods Inc. (TSXV:OGO)(OTCQX:OGOFF)(FSE:OGF0) is a Canadian-headquartered company supplying certified organic and fairtrade produce to leading international retailers. Organto manages global sourcing, logistics and distribution through an integrated, asset-efficient model that connects growers and consumers with transparency, sustainability and operational excellence.

Forward Looking Statements
This news release may include certain forward-looking information and statements, as defined by law including without limitation Canadian securities laws and the “safe harbor” provisions of the US Private Securities Litigation Reform Act of 1995 (“forward-looking statements”). In particular, and without limitation, this news release contains forward-looking statements respecting Organto’s business model and markets; Organto’s belief that the Company has made solid progress in the restructuring and realignment of its business focused on a clear path to profitability, sustained growth and long-term stability; Organto’s belief that its business has been repositioned for scalable, sustained growth via its integrated operations and asset efficient business; Organto’s belief that it is well positioned to expand into new products categories, new geographies and new value-added product segments; Organto’s belief that its guiding principles will allow the profitability and purpose to remain aligned; Organto’s belief that its success is underpinned by a disciplined operating culture, strong governance and a commitment to transparency at every level of is business; Organto’s belief that it is well positioned to capitalize on accelerating demand for organic and fairtrade foods; Organto’s belief that it remains focused on building a world class company focused on growing healthy foods markets with the goal of building lasting shareholder value; management’s beliefs, assumptions and expectations; and general business and economic conditions. Forward-looking statements are based on a number of assumptions that may prove to be incorrect, including without limitation assumptions about the following: the ability and time frame within which Organto’s business model will be implemented and product supply will be increased; cost increases; dependence on suppliers, partners, and contractual counter-parties; changes in the business or prospects of Organto; unforeseen circumstances; risks associated with the organic produce business generally, including inclement weather, unfavorable growing conditions, low crop yields, variations in crop quality, spoilage, import and export laws, and similar risks; transportation costs and risks; general business and economic conditions; and ongoing relations with distributors, customers, employees, suppliers, consultants, contractors, and partners. The foregoing list is not exhaustive and Organto undertakes no obligation to update any of the foregoing except as required by law.

SOURCE: Organto Foods, Inc.

View the original press release on ACCESS Newswire

SIOUX FALLS, SD / ACCESS Newswire / December 2, 2025 / Avel eCare is pleased to announce the appointment of Pat Gundersen as its new Chief Revenue Officer, bringing more than twenty years of leadership experience in healthcare, healthcare technology, and go-to-market strategy.

Gundersen is a seasoned C-Suite leader known for building high-performing teams, strengthening client relationships, and accelerating growth for healthcare technology and service organizations. His background includes guiding sales, client success, and strategic partnership functions while helping companies expand their market presence in an evolving healthcare landscape.

Throughout his career, Gundersen has demonstrated a talent for uniting clinical, operational, and commercial teams around shared goals. He is recognized for:

• GTM strategy and execution that helps organizations launch new offerings with clarity and confidence

• Strategic partnerships that advance innovation and improve customer outcomes

• Client retention frameworks built around strong relationships and consultative support

• Cross-functional collaboration with product, marketing, and clinical leaders to align solutions with customer needs

• Data-driven decision making that sharpens forecasting, strengthens revenue planning, and elevates market differentiation

• Mergers and acquisitions leadership, including the integration of multiple acquisition partners and participation in complex organizational transitions

“Pat brings a rare combination of strategic insight, operational depth, and a deep understanding of the healthcare environment,” said Doug Duskin, Chief Executive Officer of Avel eCare. “His ability to cultivate strong client partnerships and grow teams aligns perfectly with our mission to support hospitals, clinics, EMS teams, and communities nationwide.”

Gundersen joins Avel at a time of continued expansion across its ten telemedicine service lines, including emergency, behavioral health, virtual nursing, ICU, pharmacy, school health, and more. His leadership will help accelerate Avel’s work to advance access to care, support overburdened clinical teams, and deliver reliable, patient-centered telemedicine.

“I have long admired Avel’s commitment to serving clinicians and patients in the moments that matter most,” said Gundersen. “The team’s culture, innovation, and dedication to quality set the standard for virtual care. I am excited to help expand this impact and support the partners who rely on Avel every day.”

Gundersen will oversee revenue strategy, business development, client management, and the continued growth of Avel’s national footprint.

About Avel eCare
Avel eCare is a proven telemedicine partner that supports healthcare teams with reliable, real-time clinical expertise. With more than thirty years of experience delivering virtual care, Avel provides hospitals, clinics, EMS agencies, schools, and long-term care facilities with immediate access to board-certified physicians, advanced practice providers, nurses, pharmacists, and behavioral health experts. Avel’s ten service lines help reduce transfers, support clinicians, enhance patient outcomes, and bring high-quality care to communities across the nation. Learn more at www.avelecare.com.

Contact:

Jessica Gaikowski, Director of Marketing & Communications
media@avelecare.com | 605.606.0150

Learn more at www.avelecare.com

SOURCE: Avel eCare

View the original press release on ACCESS Newswire

NEW YORK, NY / ACCESS Newswire / November 25, 2025 / The gold market has always relied on external verification. Inspectors examined surfaces. Traders checked paperwork. Vault operators reconciled bar lists by hand. The technology behind those steps changed only marginally over the past century. That static approach created the environment where

The industry is finally moving from external checks to internal identity. SMX (NASDAQ:SMX) is entering the 2025 DMCC Precious Metals Conference with a system designed to embed verification into the material itself. It’s a technology-first shift that alters how the market can function.

Dubai is the right stage for that transformation. The DMCC is a global center for modern commodities trade by prioritizing digital systems, traceable workflows, and higher standards for responsible conduct. Under the leadership of Ahmed Bin Sulayem, the organization has consistently adopted technologies that strengthen the integrity of the sectors it oversees. The precious metals industry within the DMCC ecosystem expects tools that keep pace with global trade.

Replacing Legacy Systems with a Technology-First Approach

That’s because legacy methods no longer keep up with the volume, speed, and regulatory expectations placed on the market. A technology capable of carrying identity through each step of movement is no longer a luxury. It’s a requirement for a system that has outgrown its traditional foundation. SMX addresses that requirement with technology that operates at the molecular level, embedding a Physical-to-Digital link that creates an identity inseparable from the metal.

It remains stable under heat, pressure, and long-term storage, providing every participant in the chain with a consistent reference point. Refiners can validate output without relying exclusively on surface markings. Vaults can confirm the authenticity of their inventory at any time. Traders can execute transactions with confidence that the asset they are handling is the same asset that entered the system.

Even established service providers in the region, including Brink’s, have shown interest in how identity systems like this can reinforce their own operational frameworks. The market is moving toward solutions that embed truth at the material level. SMX built its technology specifically for that purpose.

Identity as Infrastructure

The Physical to Digital Link operates as more than a verification tool. It becomes infrastructure the moment it enters the value chain. A bar marked at the refinery maintains its identity throughout transport, storage, and trade. That identity is not dependent on a label, a barcode, or a certificate. It is not influenced by inspection conditions or subjective interpretation. It is an internal characteristic. When the metal moves, the identity moves with it. That consistency gives the market a foundation that did not exist before, and it changes how organizations manage risk and design their workflows.

This type of identity infrastructure aligns with DMCC priorities. The center has invested heavily in raising global standards across the commodities it oversees. It attracts institutions that want confidence in the assets they handle and transparency in their operational environment. A technology that gives each bar a permanent identity supports every part of that strategy. It reduces friction between market participants. It minimizes disputes during settlement. It increases audit trail accuracy without requiring additional administrative layers. It is a bottom-up improvement that strengthens every top-down control.

This is also where SMX stands apart. Many companies in the metals ecosystem have attempted to solve visibility issues by adding additional documentation or digital recordkeeping. SMX approaches the challenge from within the material rather than around it. By starting at the molecular level, SMX technology bypasses the limitations that have historically led to inconsistent identity. It creates a system that the market can build on regardless of location, handler, or trading platform. As the global gold sector seeks to modernize without sacrificing efficiency, technologies that operate with this degree of permanence become indispensable. At the right time.

A New Standard for Precision in Precious Metals

Technological advancement in the gold market has always been incremental. Scales became more accurate. Testing methods improved. Reporting systems digitized. None of those developments changed the fundamental structure behind how identity was established. SMX’s technology does. It replaces a chain of subjective assessment with a chain of measurable facts. That redefines how institutions can evaluate risk, price assets, and manage operational exposure. It also serves the growing expectation that responsible sourcing and a clear chain of custody must be verifiable rather than assumed.

Dubai’s prominence amplifies this shift. The DMCC Precious Metals Conference draws institutions that recognize the market is entering a transition period. They understand that the next decade will be shaped by the technologies that provide certainty at scale. SMX is entering that environment with a system already demonstrated in major gold hubs, including Dubai, where even long-standing logistics partners have seen its value. The market does not need promises. It needs tools that function under the pressures of real trade flows. SMX’s identity technology delivers that reliability.

As the conference unfolds, one reality is becoming crystal clear. The gold market is no longer defined by how the metal looks on the surface. It’s defined by what the material carries within it. SMX built a system that gives the world’s most trusted asset a way to prove itself at every stage of its journey. It’s a technology-first approach that brings precision, accountability, and modern infrastructure to a sector ready for change. The next chapter of the gold market will be written by the companies that make verification part of the asset. SMX is arriving at DMCC prepared to lead that shift.

About SMX

As global businesses face new and complex challenges relating to carbon neutrality and meeting new governmental and regional regulations and standards, SMX is able to offer players along the value chain access to its marking, tracking, measuring and digital platform technology to transition more successfully to a low-carbon economy.

Forward-Looking Statements

The information in this press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, statements regarding expectations, hopes, beliefs, intentions or strategies regarding the future. In addition, any statements that refer to projections, forecasts or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. The words “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “forecast,” “intends,” “may,” “will,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. Forward-looking statements in this press release may include, for example: matters relating to the Company’s fight against abusive and possibly illegal trading tactics against the Company’s stock; successful launch and implementation of SMX’s joint projects with manufacturers and other supply chain participants of steel, rubber and other materials; changes in SMX’s strategy, future operations, financial position, estimated revenues and losses, projected costs, prospects and plans; SMX’s ability to develop and launch new products and services, including its planned Plastic Cycle Token; SMX’s ability to successfully and efficiently integrate future expansion plans and opportunities; SMX’s ability to grow its business in a cost-effective manner; SMX’s product development timeline and estimated research and development costs; the implementation, market acceptance and success of SMX’s business model; developments and projections relating to SMX’s competitors and industry; and SMX’s approach and goals with respect to technology. These forward-looking statements are based on information available as of the date of this press release, and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties. Accordingly, forward-looking statements should not be relied upon as representing views as of any subsequent date, and no obligation is undertaken to update forward-looking statements to reflect events or circumstances after the date they were made, whether as a result of new information, future events or otherwise, except as may be required under applicable securities laws. As a result of a number of known and unknown risks and uncertainties, actual results or performance may be materially different from those expressed or implied by these forward-looking statements. Some factors that could cause actual results to differ include: the ability to maintain the listing of the Company’s shares on Nasdaq; changes in applicable laws or regulations; any lingering effects of the COVID-19 pandemic on SMX’s business; the ability to implement business plans, forecasts, and other expectations, and identify and realize additional opportunities; the risk of downturns and the possibility of rapid change in the highly competitive industry in which SMX operates; the risk that SMX and its current and future collaborators are unable to successfully develop and commercialize SMX’s products or services, or experience significant delays in doing so; the risk that the Company may never achieve or sustain profitability; the risk that the Company will need to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; the risk that the Company experiences difficulties in managing its growth and expanding operations; the risk that third-party suppliers and manufacturers are not able to fully and timely meet their obligations; the risk that SMX is unable to secure or protect its intellectual property; the possibility that SMX may be adversely affected by other economic, business, and/or competitive factors; and other risks and uncertainties described in SMX’s filings from time to time with the Securities and Exchange Commission.

Contact: info@securitymattersltd.com

SOURCE: SMX (Security Matters) Public Limited

View the original press release on ACCESS Newswire

New Analysis Reveals Real Hourly Pay is Falling Double-Digits Behind Inflation in Major Metros, Fueling a Localized Affordability Crisis and the Most Geographically Uneven Holiday Earnings Season Since the Pandemic

SAN FRANCISCO, CA / ACCESS Newswire / December 2, 2025 / As businesses gear up for the holiday rush, a new Instawork analysis reveals the widest affordability declines are now concentrated in San Francisco and Seattle, where real hourly pay has fallen furthest behind inflation since early 2022.

By contrast, Atlanta and New York have swung into positive real-wage territory, making them the most affordable major metros heading into the holidays. Chicago sits squarely in the middle, though worsening year-over-year.

Pay Index Winners and Losers

Hourly wages on Instawork have risen 13.65% since February 2022, but inflation rose faster – 14.81% – confirming that real wages nationally have slipped behind rising prices.

But, importantly, the national average masks a hyper-local labor market reality: These affordability challenges vary dramatically by metro area, widening the gap between what workers earn and the price of everyday essentials.

How to Read the Data:

The percentages represent the gap between local wage growth and inflation (Consumer Price Index or CPI) since early 2022.

Specifically:

A negative number = wages are losing to inflation.

A positive number = wages are outpacing inflation.

Hardest-Hit Markets: Largest Declines in Real Purchasing Power

Here’s where the gap between wage growth and inflation has widened the most since February 2022 – and where workers are staying closer to even.

San Francisco: -18.94%
Now the most expensive major metro. Affordability eroded sharply over the past year, driven by elevated services inflation and cooling wage growth in events and logistics.

Seattle: -14.91%
Still deeply underwater. Tech-sector cooling and softer warehouse demand slowed wage gains while living costs continued to rise.

Middle Tier: Real Wages Eroding, But Not Collapsing

Chicago: -9.97%
Real earnings are slipping faster year over year. Wage growth has not kept pace with local prices, particularly across warehouse and hospitality segments.

Most Resilient Markets: Real Purchasing Power Improving

Atlanta: +5.34%
One of the few markets beating inflation. Strong logistics infrastructure, film production cycles, and warehouse competition are pushing wages ahead of prices.

New York City: +1.40%
One of the biggest turnarounds in the country. Wage growth has finally overtaken inflation, boosted by hospitality demand, warehousing activity, and sharper peak-season staffing discipline.

“The labor market isn’t one story – it’s five very different ones,” said Ashwin Somakur, Senior Economics Analyst at Instawork. “In some cities, a paycheck stretches less than ever. In others, wages are finally beating inflation. That split is changing how businesses staff – and how workers earn – in real time.

“Where affordability gaps are widest, companies are leaning on flexible labor to stay agile, and workers are taking extra shifts to keep up. It’s the clearest sign yet that flexibility is no longer optional – it’s the adjustment mechanism in a high-cost economy.”

Signals for 2026: What the Wage-Inflation Gap Suggests for the Year Ahead

Instawork’s analysis points to three early trends that could shape local labor markets in 2026.

1. Stable Wages May Attract New Investment

Cities like Atlanta and New York, where real wages have held steady with inflation, could become more attractive for logistics, hospitality, and events investment next year. Stable real wages often signal a healthier, more predictable balance between labor supply, demand, and pricing pressure.

2. Flexible Staffing as a Volatility Hedge

As businesses face unpredictable consumer spending and cost pressure, more are relying on shift-based staffing to precisely match labor to real-time demand. This allows employers to stay responsive without the risk of committing to permanent headcount changes.

3. Real-Time Staffing is the New Competitive Advantage

Instawork filled ~95% of shifts in 2025, often within hours – giving operators a clear, fast way to match labor to real-time needs and compete in unpredictable markets.

About the Instawork Quarterly Pay Index

The Quarterly Pay Index measures the relationship between hourly wages and consumer prices across key U.S. metros, providing one of the most accurate real-time views of current labor market dynamics. All series are indexed to February 2022 (100), with real-wage change calculated as wage growth minus the Consumer Price Index (CPI). Data sources include Instawork transactions (2022-2025), and The Bureau of Labor Statistics, including the Employer Cost Index and Consumer Price Index.

About Instawork

Instawork is the leading AI-powered marketplace in the U.S. and Canada, connecting local businesses with more than nine million skilled hourly professionals across hospitality, industrial, and retail. With its network of verified professionals and industry-leading trust and safety, Instawork helps companies like DoorDash, Hilton, Alibaba, and Walmart scale staffing with speed and confidence.

Our top-rated app attracts the largest pool of talent by offering flexibility, competitive pay, and meaningful opportunities for advancement – keeping businesses fully staffed and operational in fast-changing labor markets.

SOURCE: Instawork

Related Documents:

• 2025 Dec Quarterly Pay Index .pdf

View the original press release on ACCESS Newswire

VANCOUVER, BRITISH COLUMBIA / ACCESS Newswire / December 2, 2025 / American Critical Minerals Corp. (“American Critical Minerals” or the “Company“) (CSE:KCLI)(OTCQB:APCOF)(FRANKFURT:2P30) is pleased to provide an update on planning and preparations for its upcoming initial drill program at the Green River Potash and Lithium Project in Utah’s Paradox Basin.

Highlights:

• After recently closing a Bought Deal Offering (including Full Exercise of the Underwriter’s Option) and Concurrent Non-Brokered Offering for aggregate gross proceeds of approximately $7,451,000, the Company is capitalized to pay final bonding and launch drilling;

• With the appointment of Dean Pekeski and with the existing Technical and Advisory Team, the Company now has the inhouse expertise and technical capability to drill and develop this Project;

• TheCompany has 3 Drill Holes within its State of Utah Potash Mineral Leases (“SITLA Leases“) which are fully permitted and bonded for drilling.

• The Company has 4 drill holes, within its recently granted BLM Potash Exploration Licenses, which are authorized, subject to Bonding, under its approved Plan of Operations (With the US Government Shut Down now concluded, the final bonding process is underway and should be completed shortly);

• Drill Target selection is complete based on recommendations from the Company’s Technical Team and the Company’s recently filed NI 43-101 Technical Report prepared by Agapito Associates;

• Initial Drill Program (2-3 holes targeted) is designed to validate historic drill data and test, through coring and brine sampling, key Potash Horizons as well as Clastic Zones for Lithium and Bromine in the Paradox & Leadville Formations;

• Initial Drill Program is also designed to position the Company to complete Maiden Resource Estimates (“MREs“) and Pre-Feasibility Studies (“PFS“) or Preliminary Economic Assessments (“PEA“) for Potash, Lithium and Bromine;

• Drill Contractor evaluation and selection process is advancing to ensure execution of the appropriate and optimal drill program for validating historic oil and gas well data across the Project’s 32,530 acre land package; and

• The Company is targeting Q1, 2026 for mobilization of site preparation and drilling.

Simon Clarke, President and CEO, stated: “With our recent financing closed and Dean Pekeski now on board as Senior Advisor, we are driving forward with our Phase 1 Drill Program. The detailed approach outlined in our recently filed 43-101 Technical Report provides a clear roadmap for confirming the historic data from 22 oil and gas wells within and adjacent to our Project. This will enable Maiden Resource Estimates and Pre-Feasibility Studies / Preliminary Economic Assessments for Potash, Lithium and Bromine, thereby confirming that nearby potash production and lithium pilot operations are indeed evidence of the potential of our Project.

We are taking the time to ensure that we have the right contractors, equipment specifications, and operational plans in place to execute this key program as efficiently and safely as possible while optimizing results. Our focus is on delivering high-quality confirmation drilling that will validate historic data and enable us to drive the Project through development and beyond.”

Market Awareness Program

The Company also announces that it has amended its existing engagement with Machai Capital Inc. (“Machai“), to further expand its digital marketing and market awareness initiatives as the Company moves to launch its Phase 1 Drill Program. Under the amended terms, the budget allocated to Machai has been increased by an additional $500,000. Machai will continue to provide comprehensive digital marketing services, including the development and execution of in-depth campaigns focused on corporate branding, investor education, market awareness, and social media and e-mail outreach, all as agreed by the Company.

Machai remains an arm’s-length marketing, advertising, and public awareness firm based in Vancouver, B.C. The engagement is for a term of up to 12 months, ending September 18, 2026, and the Company does not intend to issue any securities to Machai as consideration for their services. For further information regarding the engagement of Machai, readers are encouraged to review the news release issued by the Company on September 23, 2025.

About American Critical Minerals’ Green River Potash and Lithium Project

The Green River Potash and Lithium Project is situated within Utah’s highly productive Paradox Basin, located 20 miles northwest of Moab, Utah. It has significant logistical advantages including close proximity to major rail hubs, airport, roads, water, towns and labour markets. It also benefits from close proximity to the agricultural and industrial heartland of America and numerous potential end-users for its products.

The history of oil and gas production across the Paradox Basin provides geologic data from historic wells across the Project, and the wider Basin, validating and de-risking the potential for high grade potash and large amounts of contained lithium. Wells in and around the project reported lithium up to 500 ppm, bromine up to 6,100 ppm and boron up to 1,260 ppm (Gilbride & Santos, 2012). This data is reinforced by nearby potash production and the advanced stage of neighbouring lithium projects. The Paradox Basin is believed to contain up to 56 billion tonnes of lithium brines, potentially the largest such resource in US (Source:AnsonFastmarketsPresentation- https://wcsecure.weblink.com.au/pdf/ASN/02823465.pdf ).

The Company’s National Instrument 43-101 – Standards of Disclosure for Mineral Projects (“NI 43-101“) Potash Exploration Target consists of 500 million to 950 million tonnes of sylvinite (the most important source for the production of potash in North America) grading from 12% to 18% potassium oxide based on elog (eK2O=19% to 29% potassium chloride based on elog (eKCl)). Its Exploration Targets for Lithium and Bromine are 2.1 billion cubic meters (brine volume) grading from 71.6 to 216.3 parts per million lithium; and 2.1 billion cubic meters (brine volume) grading from 3,656 to 4,741 parts per million bromine.**

The Company holds a 100% interest in eleven State of Utah (“SITLA“) mineral and minerals salt leases covering approximately 7,050 acres, 1,094 federal lithium brine claims (BLM Placer Claims) covering 21,150 acres, and 11 federal (BLM) potash prospecting permits covering approximately 25,480 acres. Through these leases, permits and claims the Company has the ability to explore for potash, lithium and potential by-products across the entire Green River Project (approx. 32,530 acres). The Company is authorized to drill a total of 7 drill holes across the Project (pending bonding the recently approved 4 drill holes).

Intrepid Potash, Inc. is America’s largest potash company and only U.S. domestic potash producer and currently produces potash from its nearby Moab Solution Mine, which the Company believes provides strong evidence of stratigraphic continuity within this part of the Paradox Basin (www.intrepidpotash.com). Anson Resources Ltd. has advanced lithium development projects contiguous to the northern boundary of our Green River Project and neighbouring to the south. Anson has a large initial resource, robust definitive feasibility study and has recently completed successful piloting operations through its partnership with Koch Technology Solutions, as well as an offtake agreement with LG Energy Solution. The Anson exploration targets encompass the combined Mississippian Leadville Formation and the Pennsylvanian Paradox Formation brine-bearing clastic layers, which also underlie American Critical Minerals’ entire project area (www.ansonresources.com)*.

In 2022, the U.S. imported approx. 96.5% of its annual potash requirements with domestic producers receiving a higher sales price due to proximity to market (intrepidpotash.com/ August 15, 2024, Investor Presentation). In March 2024, the US Senate introduced a bill to include key fertilizers and potash on the US Department of Interior list of Critical Minerals which already includes lithium, and this process is well advanced with potash being added to the USGS Draft Critical Minerals List. In August 2025. Recent market estimates suggest that the global potash market is over US$50 billion annually and growing at a compound annual growth rate (“CAGR”) of close to 5%. Annual lithium demand is now estimated to be over 1 million tonnes globally and continuing to grow rapidly***.

****Exploration Targets are conceptual in nature and there has been insufficient exploration to define them as Mineral Resources, and, while reasonable potential may exist, it is uncertain whether further exploration will result in the determination of a Mineral Resource under NI 43-101.

Qualified Person

The technical content of this news release has been reviewed and approved by Dean Besserer, P.Geo., the Chief Operations Officer of the Company and a qualified person for the purposes of NI 43-101.

On behalf of the Board of Directors

Simon Clarke, President & CEO
Contact: (604)-551-9665

*American Critical Minerals’ management cautions that results or discoveries on properties in proximity to the American Critical Minerals’ properties may not necessarily be indicative of the presence of mineralization on the Company’s properties.

**A report titled “NI 43-101 Technical Report – Green River Potash and Lithium Project, Grand County, Utah, USA”, prepared by Agapito Associates Inc., and dated October 27, 2025, quantifies the Green River Potash Project’s potash, lithium and bromine exploration potential in the form of NI 43-101 Exploration Targets. The Exploration Target estimate was prepared in accordance with NI 43-101. It should be noted that Exploration Targets are conceptual in nature and there has been insufficient exploration to define them as Mineral Resources, and, while reasonable potential may exist, it is uncertain whether further exploration will result in the determination of a Mineral Resource under NI 43-101. Details of the basis on which the Exploration Targets have been determined is included in the Report. The Exploration Target stated in the Report is not being reported as part of any Mineral Resource or Mineral Reserve. A copy of the report can be accessed on both SEDAR+ (www.sedarplus.ca) and the corporate website for the Company: www.acmineralscorp.com.

***United States Geological Survey, Mineral Commodity Summaries, January 2024 (https://pubs.usgs.gov/periodicals/mcs2024/mcs2024-potash.pdf).

CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING INFORMATION

This news release contains forward-looking information or forward-looking statements within the meaning of applicable securities legislation. All statements, other than statements of historical fact, are forward-looking statements and are based on expectations, estimates and projections as at the date of this news release. Any statement that involves discussion with respect to predictions, expectations, beliefs, plans, projections, objectives, assumptions, future events or performance (often, but not always using phrases such as “plans”, “expects”, “is expected”, “budget”, “scheduled”, “estimates”, “forecasts”, “intends”, “anticipates”, or “believes” or variations (including negative variations) of such words and phrases, or state that certain actions, events or results “may”, “could”, “would”, “might” or “will” be taken, occur or be achieved) are not statements of historical fact and may be forward-looking statements. In this news release, forward-looking statements relate, among other things, to: use of proceeds; statements about exploration targets; goals of the Company; magnitude or quality of mineral deposits; anticipated advancement of mineral properties or programs; and future exploration prospects.

Although the Company believes that such statements are reasonable, it can give no assurances that such expectations will prove to be correct. All such forward-looking statements are based on certain assumptions and analyses made by the Company in light of their experience and perception of historical trends, current conditions and expected future developments, as well as other factors management believes are appropriate in the circumstances. Forward-looking statements also involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of the Company to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Important factors that could cause actual results to differ from this forward-looking information include those described under the heading “Risks and Uncertainties” in the Company’s most recently filed MD&A.

Forward-looking information contained herein are made as of the date of this news release and the Company does not intend, and expressly disclaims any obligation to, update or revise the forward-looking information contained in this news release, except as required by law. There can be no assurance that forward-looking statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements.

Neither the Canadian Securities Exchange nor its Market Regulator (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release.

SOURCE: American Critical Minerals Corp.

View the original press release on ACCESS Newswire

Phase 1 results show that SUL-238 is safe, well-tolerated, and demonstrates favorable pharmacokinetics with high CSF penetration in healthy elderly volunteers, supporting its advancement into further clinical development for Alzheimer’s and other neurodegenerative diseases.

ANKARA, TR / ACCESS Newswire / December 2, 2025 / GEN Pharmaceuticals (GENIL.IS), Türkiye’s leading specialty pharmaceutical company, has announced new positive results from its Phase 1 clinical trial evaluating the safety, tolerability, and pharmacokinetics (PK) of first-in-class, novel orally administered mitochondria-directed drug candidate SUL-238 in healthy elderly volunteers. The findings were presented at the 18^th Clinical Trials on Alzheimer’s Disease (CTAD) in San Diego, CA (United States) today.

SUL-238 was originally discovered by Sulfateq and has since been further developed through a collaborative effort of Sulfateq and GEN as a novel therapeutic in neurodegenerative diseases.

This Phase 1 randomized, double-blind, placebo-controlled study evaluated the safety, tolerability, and pharmacokinetics (PK) after multiple-ascending doses (MAD) of orally administered SUL-238 in healthy elderly men and women (aged ≥40 years). The study included two cohorts with a treatment period of 14 days and a safety follow-up through 14 days after the last dose. 15 healthy adults in each cohort were randomized in a 2:1 ratio to receive SUL-238 or placebo. Total daily dose of SUL-238 was 4000 mg (2000 mg b.i.d., first cohort) or 4500 mg (1500 mg t.i.d., second cohort). SUL-238 demonstrated an excellent safety and tolerability profile after multiple doses in both cohorts, while demonstrating a favourable PK profile and a high cerebrospinal fluid (CSF) penetration, making it a promising candidate for further clinical development in neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases.

Key Findings:

Safety in both cohorts:

• No clinically significant changes were observed in physical and neurological exams, vital signs, ECG, and clinical laboratory parameters.

• AE rates were comparable between participants receiving SUL-238 and placebo.

• All AEs were of mild intensity or considered not related to SUL-238.

First cohort PK (2000 mg b.i.d.):

• SUL-238 was rapidly absorbed with a mean time to maximum plasma concentration (T_max) reached at 1.25(±0.54) and 1.50(±0.53) hours on day 1 and day 14, respectively.

• Mean terminal elimination half-life (t_1/2) was3.50(±1.06) hours on day 14.

• Mean trough plasma concentration of SUL-238 was 39.23(±24.31) ng/mL and 41.49(±18.20) ng/mL on day 8 and day 14, respectively.

Second cohort PK (1500 mg t.i.d.):

• SUL-238 was rapidly absorbed, with a mean time to maximum plasma concentration (T_max) reached at 0.95(±0.16) and 1.00(±0.00) hours on day 1 and day 14, respectively.

• Mean terminal elimination half-life (t_1/2):3.74(±1.84) hours on day 14.

• Mean trough plasma concentration of SUL-238 was 57.98(±31.08) and 60.63(±64.14) ng/mL on day 8 and day 14, respectively.

Abidin Gülmüş, Chairman of GEN, stated:
“We’re greatly motivated by these new positive results of SUL-238 in our Phase 1 trial, which mark a key advance toward addressing Alzheimer’s disease at its biological foundation.”

Nadir Ulu, MD, PhD, Vice President of R&D at GEN, added:
“With its excellent safety and PK profile in this Multiple Ascending Dose Phase 1 trial, SUL-238 continues to represent a very strong drug candidate for further clinical development aimed at meeting the critical unmet needs in neurodegenerative diseases, including Alzheimer’s disease.

About SUL-238
SUL-238 is a novel, first-in-class, hibernation-derived small molecule designed to target mitochondria, the ‘powerhouse’ of the cell. SUL-238 supports mitochondrial bioenergetics via complex I/IV activation and enhances mitochondrial function in various preclinical models for neurodegenerative, cardiovascular, and renal diseases, as well as in accelerated aging. SUL-238 exhibits the capability to cross the blood-brain barrier and has undergone extensive safety evaluation in preclinical and clinical Phase 1 studies. GEN licenses SUL-238 from Sulfateq B.V. for neurodegenerative disease applications.

About GEN:
Founded in 1998, GEN is Türkiye’s leading specialty pharmaceutical company, focused on developing innovative therapies across multiple therapeutic areas. Through significant R&D investments and global collaborations, GEN is committed to advancing healthcare worldwide. The company develops and manufactures high-quality, competitive products at its GMP-certified production facility and continues its bold efforts in original drug development via two dedicated R&D centers.

About Sulfateq:

Sulfateq B.V. is an early-stage Dutch biotech company that fosters strategic collaborations with academic and industrial research centres to accelerate the development of innovative new medicines. It has developed a novel class of small molecules, the SUL-compounds, that maintain mitochondrial health.

For more information:
www.genilac.com.tr
www.sulfateqbv.com

Contact Information

Bulutay Güneş
Sr. Head of Corporate Brand
b.gunes@genilac.com

Fatih Gören
Investor Relations Manager
f.goren@genilac.com

SOURCE: GEN İlaç ve Sağlık Ürünleri A.Ş.

View the original press release on ACCESS Newswire